Anti-CLC2A/ CLEC2A/ INPE5792 monoclonal antibody

Anti-CLC2A/ CLEC2A/ INPE5792 antibody for FACS & in-vivo assay

Target products collectionGo to CLEC2A/CLEC2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0293-Ab-1/ GM-Tg-hg-MP0293-Ab-2Anti-Human CLEC2A monoclonal antibodyHuman
GM-Tg-rg-MP0293-Ab-1/ GM-Tg-rg-MP0293-Ab-2Anti-Rat CLEC2A monoclonal antibodyRat
GM-Tg-mg-MP0293-Ab-1/ GM-Tg-mg-MP0293-Ab-2Anti-Mouse CLEC2A monoclonal antibodyMouse
GM-Tg-cynog-MP0293-Ab-1/ GM-Tg-cynog-MP0293-Ab-2Anti-Cynomolgus/ Rhesus macaque CLEC2A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0293-Ab-1/ GM-Tg-felg-MP0293-Ab-2Anti-Feline CLEC2A monoclonal antibodyFeline
GM-Tg-cang-MP0293-Ab-1/ GM-Tg-cang-MP0293-Ab-2Anti-Canine CLEC2A monoclonal antibodyCanine
GM-Tg-bovg-MP0293-Ab-1/ GM-Tg-bovg-MP0293-Ab-2Anti-Bovine CLEC2A monoclonal antibodyBovine
GM-Tg-equg-MP0293-Ab-1/ GM-Tg-equg-MP0293-Ab-2Anti-Equine CLEC2A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0293-Ab-1/ GM-Tg-hg-MP0293-Ab-2; GM-Tg-rg-MP0293-Ab-1/ GM-Tg-rg-MP0293-Ab-2;
GM-Tg-mg-MP0293-Ab-1/ GM-Tg-mg-MP0293-Ab-2; GM-Tg-cynog-MP0293-Ab-1/ GM-Tg-cynog-MP0293-Ab-2;
GM-Tg-felg-MP0293-Ab-1/ GM-Tg-felg-MP0293-Ab-2; GM-Tg-cang-MP0293-Ab-1/ GM-Tg-cang-MP0293-Ab-2;
GM-Tg-bovg-MP0293-Ab-1/ GM-Tg-bovg-MP0293-Ab-2; GM-Tg-equg-MP0293-Ab-1/ GM-Tg-equg-MP0293-Ab-2
Products NameAnti-CLEC2A monoclonal antibody
Formatmab
Target NameCLEC2A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CLEC2A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CLC2A/ CLEC2A/ INPE5792 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0293
    Target NameCLEC2A
    Gene ID387836,722314,101085219,111774040
    Gene Symbol and SynonymsCLEC2A,INPE5792,KACL,PILAR,UNQ5792
    Uniprot AccessionQ6UVW9
    Uniprot Entry NameCLC2A_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000188393
    Target ClassificationN/A

    The target: CLEC2A, gene name: CLEC2A, also named as INPE5792, KACL, PILAR, UNQ5792. CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).[supplied by OMIM, May 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.