- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-CLC7A/ CLEC7A/ BGR monoclonal antibody
Anti-CLC7A/ CLEC7A/ BGR antibody for FACS & in-vivo assay
Go to CLEC7A/CLEC7A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0301-Ab-1/ GM-Tg-hg-MP0301-Ab-2 | Anti-Human CLEC7A monoclonal antibody | Human |
| GM-Tg-rg-MP0301-Ab-1/ GM-Tg-rg-MP0301-Ab-2 | Anti-Rat CLEC7A monoclonal antibody | Rat |
| GM-Tg-mg-MP0301-Ab-1/ GM-Tg-mg-MP0301-Ab-2 | Anti-Mouse CLEC7A monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0301-Ab-1/ GM-Tg-cynog-MP0301-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CLEC7A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0301-Ab-1/ GM-Tg-felg-MP0301-Ab-2 | Anti-Feline CLEC7A monoclonal antibody | Feline |
| GM-Tg-cang-MP0301-Ab-1/ GM-Tg-cang-MP0301-Ab-2 | Anti-Canine CLEC7A monoclonal antibody | Canine |
| GM-Tg-bovg-MP0301-Ab-1/ GM-Tg-bovg-MP0301-Ab-2 | Anti-Bovine CLEC7A monoclonal antibody | Bovine |
| GM-Tg-equg-MP0301-Ab-1/ GM-Tg-equg-MP0301-Ab-2 | Anti-Equine CLEC7A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0301-Ab-1/ GM-Tg-hg-MP0301-Ab-2; GM-Tg-rg-MP0301-Ab-1/ GM-Tg-rg-MP0301-Ab-2; GM-Tg-mg-MP0301-Ab-1/ GM-Tg-mg-MP0301-Ab-2; GM-Tg-cynog-MP0301-Ab-1/ GM-Tg-cynog-MP0301-Ab-2; GM-Tg-felg-MP0301-Ab-1/ GM-Tg-felg-MP0301-Ab-2; GM-Tg-cang-MP0301-Ab-1/ GM-Tg-cang-MP0301-Ab-2; GM-Tg-bovg-MP0301-Ab-1/ GM-Tg-bovg-MP0301-Ab-2; GM-Tg-equg-MP0301-Ab-1/ GM-Tg-equg-MP0301-Ab-2 |
| Products Name | Anti-CLEC7A monoclonal antibody |
| Format | mab |
| Target Name | CLEC7A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CLEC7A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CLC7A/ CLEC7A/ BGR VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP004926 | human CLEC7A Lentivirus plasmid |
| ORF Viral Vector | vGMLP004926 | human CLEC7A Lentivirus particle |
| ORF Viral Vector | pGMLPm003538 | mouse Clec7a Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003538 | mouse Clec7a Lentivirus particle |
Target information
| Target ID | GM-MP0301 |
| Target Name | CLEC7A |
| Gene ID | 64581,56644,502902,574356,611385,101083523,532865,100053863 |
| Gene Symbol and Synonyms | beta-GR,BGR,CANDF4,CD369,CLEC7A,Clec7b,CLECSF12,DECTIN1,RGD1565140,SCARE2 |
| Uniprot Accession | Q9BXN2,Q8HZR8,Q49BZ4 |
| Uniprot Entry Name | CLC7A_HUMAN,CLC7A_MACMU,CLC7A_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000172243 |
| Target Classification | N/A |
The target: CLEC7A, gene name: CLEC7A, also named as BGR, CANDF4, CD369, CLECSF12, DECTIN1, SCARE2. This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
