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Anti-CLMP/ ACAM/ ASAM monoclonal antibody
Anti-CLMP/ ACAM/ ASAM antibody for FACS & in-vivo assay
Go to CLMP/CLMP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0304-Ab-1/ GM-Tg-hg-MP0304-Ab-2 | Anti-Human CLMP monoclonal antibody | Human |
| GM-Tg-rg-MP0304-Ab-1/ GM-Tg-rg-MP0304-Ab-2 | Anti-Rat CLMP monoclonal antibody | Rat |
| GM-Tg-mg-MP0304-Ab-1/ GM-Tg-mg-MP0304-Ab-2 | Anti-Mouse CLMP monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0304-Ab-1/ GM-Tg-cynog-MP0304-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CLMP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0304-Ab-1/ GM-Tg-felg-MP0304-Ab-2 | Anti-Feline CLMP monoclonal antibody | Feline |
| GM-Tg-cang-MP0304-Ab-1/ GM-Tg-cang-MP0304-Ab-2 | Anti-Canine CLMP monoclonal antibody | Canine |
| GM-Tg-bovg-MP0304-Ab-1/ GM-Tg-bovg-MP0304-Ab-2 | Anti-Bovine CLMP monoclonal antibody | Bovine |
| GM-Tg-equg-MP0304-Ab-1/ GM-Tg-equg-MP0304-Ab-2 | Anti-Equine CLMP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0304-Ab-1/ GM-Tg-hg-MP0304-Ab-2; GM-Tg-rg-MP0304-Ab-1/ GM-Tg-rg-MP0304-Ab-2; GM-Tg-mg-MP0304-Ab-1/ GM-Tg-mg-MP0304-Ab-2; GM-Tg-cynog-MP0304-Ab-1/ GM-Tg-cynog-MP0304-Ab-2; GM-Tg-felg-MP0304-Ab-1/ GM-Tg-felg-MP0304-Ab-2; GM-Tg-cang-MP0304-Ab-1/ GM-Tg-cang-MP0304-Ab-2; GM-Tg-bovg-MP0304-Ab-1/ GM-Tg-bovg-MP0304-Ab-2; GM-Tg-equg-MP0304-Ab-1/ GM-Tg-equg-MP0304-Ab-2 |
| Products Name | Anti-CLMP monoclonal antibody |
| Format | mab |
| Target Name | CLMP |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CLMP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CLMP/ ACAM/ ASAM VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP001619 | human CLMP Lentivirus plasmid |
| ORF Viral Vector | vGMLP001619 | human CLMP Lentivirus particle |
| ORF Viral Vector | pGMLPm001692 | mouse Clmp Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001692 | mouse Clmp Lentivirus particle |
Target information
| Target ID | GM-MP0304 |
| Target Name | CLMP |
| Gene ID | 79827,71566,286939,708098,489353,101092046,516565,111774236 |
| Gene Symbol and Synonyms | 9030425E11Rik,ACAM,ASAM,ASP5,CLMP,CSBM,CSBS,Ol16 |
| Uniprot Accession | Q9H6B4,Q8K1G0 |
| Uniprot Entry Name | CLMP_HUMAN,CLMP_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000166250 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: CLMP, gene name: CLMP, also named as ACAM, ASAM, CSBM, CSBS. This gene encodes a type I transmembrane protein that is localized to junctional complexes between endothelial and epithelial cells and may have a role in cell-cell adhesion. Expression of this gene in white adipose tissue is implicated in adipocyte maturation and development of obesity. This gene is also essential for normal intestinal development and mutations in the gene are associated with congenital short bowel syndrome. [provided by RefSeq, Aug 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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