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Anti-CODA1/ COL13A1/ CMS19 monoclonal antibody
Anti-CODA1/ COL13A1/ CMS19 antibody for FACS & in-vivo assay
Go to COL13A1/COL13A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0322-Ab-1/ GM-Tg-hg-MP0322-Ab-2 | Anti-Human COL13A1 monoclonal antibody | Human |
| GM-Tg-rg-MP0322-Ab-1/ GM-Tg-rg-MP0322-Ab-2 | Anti-Rat COL13A1 monoclonal antibody | Rat |
| GM-Tg-mg-MP0322-Ab-1/ GM-Tg-mg-MP0322-Ab-2 | Anti-Mouse COL13A1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0322-Ab-1/ GM-Tg-cynog-MP0322-Ab-2 | Anti-Cynomolgus/ Rhesus macaque COL13A1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0322-Ab-1/ GM-Tg-felg-MP0322-Ab-2 | Anti-Feline COL13A1 monoclonal antibody | Feline |
| GM-Tg-cang-MP0322-Ab-1/ GM-Tg-cang-MP0322-Ab-2 | Anti-Canine COL13A1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0322-Ab-1/ GM-Tg-bovg-MP0322-Ab-2 | Anti-Bovine COL13A1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0322-Ab-1/ GM-Tg-equg-MP0322-Ab-2 | Anti-Equine COL13A1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0322-Ab-1/ GM-Tg-hg-MP0322-Ab-2; GM-Tg-rg-MP0322-Ab-1/ GM-Tg-rg-MP0322-Ab-2; GM-Tg-mg-MP0322-Ab-1/ GM-Tg-mg-MP0322-Ab-2; GM-Tg-cynog-MP0322-Ab-1/ GM-Tg-cynog-MP0322-Ab-2; GM-Tg-felg-MP0322-Ab-1/ GM-Tg-felg-MP0322-Ab-2; GM-Tg-cang-MP0322-Ab-1/ GM-Tg-cang-MP0322-Ab-2; GM-Tg-bovg-MP0322-Ab-1/ GM-Tg-bovg-MP0322-Ab-2; GM-Tg-equg-MP0322-Ab-1/ GM-Tg-equg-MP0322-Ab-2 |
| Products Name | Anti-COL13A1 monoclonal antibody |
| Format | mab |
| Target Name | COL13A1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-COL13A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CODA1/ COL13A1/ CMS19 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0322 |
| Target Name | COL13A1 |
| Gene ID | 1305,12817,499431,716986,609516,101098656,613849,100072695 |
| Gene Symbol and Synonyms | CMS19,COL13A1,COLXIIIA1 |
| Uniprot Accession | Q5TAT6 |
| Uniprot Entry Name | CODA1_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000197467 |
| Target Classification | N/A |
The target: COL13A1, gene name: COL13A1, also named as CMS19, COLXIIIA1. This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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