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Anti-COLQ/ CMS5/ EAD monoclonal antibody
Anti-COLQ/ CMS5/ EAD antibody for FACS & in-vivo assay
Go to COLQ/COLQ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0327-Ab-1/ GM-Tg-hg-MP0327-Ab-2 | Anti-Human COLQ monoclonal antibody | Human |
| GM-Tg-rg-MP0327-Ab-1/ GM-Tg-rg-MP0327-Ab-2 | Anti-Rat COLQ monoclonal antibody | Rat |
| GM-Tg-mg-MP0327-Ab-1/ GM-Tg-mg-MP0327-Ab-2 | Anti-Mouse COLQ monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0327-Ab-1/ GM-Tg-cynog-MP0327-Ab-2 | Anti-Cynomolgus/ Rhesus macaque COLQ monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0327-Ab-1/ GM-Tg-felg-MP0327-Ab-2 | Anti-Feline COLQ monoclonal antibody | Feline |
| GM-Tg-cang-MP0327-Ab-1/ GM-Tg-cang-MP0327-Ab-2 | Anti-Canine COLQ monoclonal antibody | Canine |
| GM-Tg-bovg-MP0327-Ab-1/ GM-Tg-bovg-MP0327-Ab-2 | Anti-Bovine COLQ monoclonal antibody | Bovine |
| GM-Tg-equg-MP0327-Ab-1/ GM-Tg-equg-MP0327-Ab-2 | Anti-Equine COLQ monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0327-Ab-1/ GM-Tg-hg-MP0327-Ab-2; GM-Tg-rg-MP0327-Ab-1/ GM-Tg-rg-MP0327-Ab-2; GM-Tg-mg-MP0327-Ab-1/ GM-Tg-mg-MP0327-Ab-2; GM-Tg-cynog-MP0327-Ab-1/ GM-Tg-cynog-MP0327-Ab-2; GM-Tg-felg-MP0327-Ab-1/ GM-Tg-felg-MP0327-Ab-2; GM-Tg-cang-MP0327-Ab-1/ GM-Tg-cang-MP0327-Ab-2; GM-Tg-bovg-MP0327-Ab-1/ GM-Tg-bovg-MP0327-Ab-2; GM-Tg-equg-MP0327-Ab-1/ GM-Tg-equg-MP0327-Ab-2 |
| Products Name | Anti-COLQ monoclonal antibody |
| Format | mab |
| Target Name | COLQ |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-COLQ benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species COLQ/ CMS5/ EAD VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP001477 | human COLQ Lentivirus particle |
| ORF Viral Vector | pGMLP001477 | human COLQ Lentivirus plasmid |
| ORF Viral Vector | pGMLPm005330 | mouse Colq Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005330 | mouse Colq Lentivirus particle |
Target information
| Target ID | GM-MP0327 |
| Target Name | COLQ |
| Gene ID | 8292,382864,29755,694331,101093134,514615,100052475 |
| Gene Symbol and Synonyms | A130034K24Rik,CMS5,COLQ,EAD |
| Uniprot Accession | Q9Y215,O35167 |
| Uniprot Entry Name | COLQ_HUMAN,COLQ_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000206561 |
| Target Classification | N/A |
The target: COLQ, gene name: COLQ, also named as CMS5, EAD. This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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