Anti-CBPD/ CPD/ GP180 monoclonal antibody

Anti-CBPD/ CPD/ GP180 antibody for FACS & in-vivo assay

Target products collectionGo to CPD/CPD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0330-Ab-1/ GM-Tg-hg-MP0330-Ab-2Anti-Human CPD monoclonal antibodyHuman
GM-Tg-rg-MP0330-Ab-1/ GM-Tg-rg-MP0330-Ab-2Anti-Rat CPD monoclonal antibodyRat
GM-Tg-mg-MP0330-Ab-1/ GM-Tg-mg-MP0330-Ab-2Anti-Mouse CPD monoclonal antibodyMouse
GM-Tg-cynog-MP0330-Ab-1/ GM-Tg-cynog-MP0330-Ab-2Anti-Cynomolgus/ Rhesus macaque CPD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0330-Ab-1/ GM-Tg-felg-MP0330-Ab-2Anti-Feline CPD monoclonal antibodyFeline
GM-Tg-cang-MP0330-Ab-1/ GM-Tg-cang-MP0330-Ab-2Anti-Canine CPD monoclonal antibodyCanine
GM-Tg-bovg-MP0330-Ab-1/ GM-Tg-bovg-MP0330-Ab-2Anti-Bovine CPD monoclonal antibodyBovine
GM-Tg-equg-MP0330-Ab-1/ GM-Tg-equg-MP0330-Ab-2Anti-Equine CPD monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0330-Ab-1/ GM-Tg-hg-MP0330-Ab-2; GM-Tg-rg-MP0330-Ab-1/ GM-Tg-rg-MP0330-Ab-2;
GM-Tg-mg-MP0330-Ab-1/ GM-Tg-mg-MP0330-Ab-2; GM-Tg-cynog-MP0330-Ab-1/ GM-Tg-cynog-MP0330-Ab-2;
GM-Tg-felg-MP0330-Ab-1/ GM-Tg-felg-MP0330-Ab-2; GM-Tg-cang-MP0330-Ab-1/ GM-Tg-cang-MP0330-Ab-2;
GM-Tg-bovg-MP0330-Ab-1/ GM-Tg-bovg-MP0330-Ab-2; GM-Tg-equg-MP0330-Ab-1/ GM-Tg-equg-MP0330-Ab-2
Products NameAnti-CPD monoclonal antibody
Formatmab
Target NameCPD
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CPD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CBPD/ CPD/ GP180 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0330
    Target NameCPD
    Gene ID1362,12874,25306,712407,480636,101081771,532189,100072234
    Gene Symbol and SynonymsCPD,D830034L15Rik,GP180
    Uniprot AccessionO75976,Q9JHW1
    Uniprot Entry NameCBPD_HUMAN,CBPD_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000108582
    Target ClassificationN/A

    The target: CPD, gene name: CPD, also named as GP180. The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.