Anti-CXL16/ CXCL16/ CXCLG16 monoclonal antibody

Anti-CXL16/ CXCL16/ CXCLG16 antibody for FACS & in-vivo assay

Target products collectionGo to CXCL16/CXCL16 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0342-Ab-1/ GM-Tg-hg-MP0342-Ab-2Anti-Human CXCL16 monoclonal antibodyHuman
GM-Tg-rg-MP0342-Ab-1/ GM-Tg-rg-MP0342-Ab-2Anti-Rat CXCL16 monoclonal antibodyRat
GM-Tg-mg-MP0342-Ab-1/ GM-Tg-mg-MP0342-Ab-2Anti-Mouse CXCL16 monoclonal antibodyMouse
GM-Tg-cynog-MP0342-Ab-1/ GM-Tg-cynog-MP0342-Ab-2Anti-Cynomolgus/ Rhesus macaque CXCL16 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0342-Ab-1/ GM-Tg-felg-MP0342-Ab-2Anti-Feline CXCL16 monoclonal antibodyFeline
GM-Tg-cang-MP0342-Ab-1/ GM-Tg-cang-MP0342-Ab-2Anti-Canine CXCL16 monoclonal antibodyCanine
GM-Tg-bovg-MP0342-Ab-1/ GM-Tg-bovg-MP0342-Ab-2Anti-Bovine CXCL16 monoclonal antibodyBovine
GM-Tg-equg-MP0342-Ab-1/ GM-Tg-equg-MP0342-Ab-2Anti-Equine CXCL16 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0342-Ab-1/ GM-Tg-hg-MP0342-Ab-2; GM-Tg-rg-MP0342-Ab-1/ GM-Tg-rg-MP0342-Ab-2;
GM-Tg-mg-MP0342-Ab-1/ GM-Tg-mg-MP0342-Ab-2; GM-Tg-cynog-MP0342-Ab-1/ GM-Tg-cynog-MP0342-Ab-2;
GM-Tg-felg-MP0342-Ab-1/ GM-Tg-felg-MP0342-Ab-2; GM-Tg-cang-MP0342-Ab-1/ GM-Tg-cang-MP0342-Ab-2;
GM-Tg-bovg-MP0342-Ab-1/ GM-Tg-bovg-MP0342-Ab-2; GM-Tg-equg-MP0342-Ab-1/ GM-Tg-equg-MP0342-Ab-2
Products NameAnti-CXCL16 monoclonal antibody
Formatmab
Target NameCXCL16
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CXCL16 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CXL16/ CXCL16/ CXCLG16 VLP (virus-like particle) (Products Developing)
    CytokineGM-Tg-g-MP0342-Ag-1chemokine (C-X-C motif) ligand 16 (CXCL16) protein
    ORF Viral VectorpGMLV000069human CXCL16 Lentivirus plasmid
    ORF Viral VectorvGMLV000069human CXCL16 Lentivirus particle
    ORF Viral VectorpGMLPm003712mouse Cxcl16 Lentivirus plasmid
    ORF Viral VectorvGMLPm003712mouse Cxcl16 Lentivirus particle


    Target information

    Target IDGM-MP0342
    Target NameCXCL16
    Gene ID58191,66102,497942,721566,607514,101093310,511671,100061442
    Gene Symbol and Synonyms0910001K24Rik,b2b498Clo,CXCL16,CXCL16v1,CXCL16v2,CXCLG16,SR-PSOX,SRPSOX,Zmynd15
    Uniprot AccessionQ9H2A7,Q6AXU5,Q29RT9
    Uniprot Entry NameCXL16_HUMAN,CXL16_RAT,CXL16_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000161921
    Target ClassificationN/A

    The target: CXCL16, gene name: CXCL16, also named as CXCLG16, SR-PSOX, SRPSOX. Enables chemokine activity. Involved in several processes, including positive regulation of cell growth; response to interferon-gamma; and response to tumor necrosis factor. Located in extracellular space. Biomarker of COVID-19 and systemic scleroderma. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.