Anti-CYBR1/ CYBRD1/ CYB561A2 monoclonal antibody

Anti-CYBR1/ CYBRD1/ CYB561A2 antibody for FACS & in-vivo assay

Target products collectionGo to CYBRD1/CYBRD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0345-Ab-1/ GM-Tg-hg-MP0345-Ab-2Anti-Human CYBRD1 monoclonal antibodyHuman
GM-Tg-rg-MP0345-Ab-1/ GM-Tg-rg-MP0345-Ab-2Anti-Rat CYBRD1 monoclonal antibodyRat
GM-Tg-mg-MP0345-Ab-1/ GM-Tg-mg-MP0345-Ab-2Anti-Mouse CYBRD1 monoclonal antibodyMouse
GM-Tg-cynog-MP0345-Ab-1/ GM-Tg-cynog-MP0345-Ab-2Anti-Cynomolgus/ Rhesus macaque CYBRD1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0345-Ab-1/ GM-Tg-felg-MP0345-Ab-2Anti-Feline CYBRD1 monoclonal antibodyFeline
GM-Tg-cang-MP0345-Ab-1/ GM-Tg-cang-MP0345-Ab-2Anti-Canine CYBRD1 monoclonal antibodyCanine
GM-Tg-bovg-MP0345-Ab-1/ GM-Tg-bovg-MP0345-Ab-2Anti-Bovine CYBRD1 monoclonal antibodyBovine
GM-Tg-equg-MP0345-Ab-1/ GM-Tg-equg-MP0345-Ab-2Anti-Equine CYBRD1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0345-Ab-1/ GM-Tg-hg-MP0345-Ab-2; GM-Tg-rg-MP0345-Ab-1/ GM-Tg-rg-MP0345-Ab-2;
GM-Tg-mg-MP0345-Ab-1/ GM-Tg-mg-MP0345-Ab-2; GM-Tg-cynog-MP0345-Ab-1/ GM-Tg-cynog-MP0345-Ab-2;
GM-Tg-felg-MP0345-Ab-1/ GM-Tg-felg-MP0345-Ab-2; GM-Tg-cang-MP0345-Ab-1/ GM-Tg-cang-MP0345-Ab-2;
GM-Tg-bovg-MP0345-Ab-1/ GM-Tg-bovg-MP0345-Ab-2; GM-Tg-equg-MP0345-Ab-1/ GM-Tg-equg-MP0345-Ab-2
Products NameAnti-CYBRD1 monoclonal antibody
Formatmab
Target NameCYBRD1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CYBRD1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CYBR1/ CYBRD1/ CYB561A2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0345
    Target NameCYBRD1
    Gene ID79901,73649,295669,694818,478796,101089456,534257,100063657
    Gene Symbol and Synonyms2210407P13Rik,CYB561A2,CYBRD1,DCYTB,FRRS3
    Uniprot AccessionQ53TN4,Q5RKJ2
    Uniprot Entry NameCYBR1_HUMAN,CYBR1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000071967
    Target ClassificationN/A

    The target: CYBRD1, gene name: CYBRD1, also named as CYB561A2, DCYTB, FRRS3. This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.