Anti-DCSTP/ DCSTAMP/ FIND monoclonal antibody

Anti-DCSTP/ DCSTAMP/ FIND antibody for FACS & in-vivo assay

Target products collectionGo to DCSTAMP/DCSTAMP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0352-Ab-1/ GM-Tg-hg-MP0352-Ab-2Anti-Human DCSTAMP monoclonal antibodyHuman
GM-Tg-rg-MP0352-Ab-1/ GM-Tg-rg-MP0352-Ab-2Anti-Rat DCSTAMP monoclonal antibodyRat
GM-Tg-mg-MP0352-Ab-1/ GM-Tg-mg-MP0352-Ab-2Anti-Mouse DCSTAMP monoclonal antibodyMouse
GM-Tg-cynog-MP0352-Ab-1/ GM-Tg-cynog-MP0352-Ab-2Anti-Cynomolgus/ Rhesus macaque DCSTAMP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0352-Ab-1/ GM-Tg-felg-MP0352-Ab-2Anti-Feline DCSTAMP monoclonal antibodyFeline
GM-Tg-cang-MP0352-Ab-1/ GM-Tg-cang-MP0352-Ab-2Anti-Canine DCSTAMP monoclonal antibodyCanine
GM-Tg-bovg-MP0352-Ab-1/ GM-Tg-bovg-MP0352-Ab-2Anti-Bovine DCSTAMP monoclonal antibodyBovine
GM-Tg-equg-MP0352-Ab-1/ GM-Tg-equg-MP0352-Ab-2Anti-Equine DCSTAMP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0352-Ab-1/ GM-Tg-hg-MP0352-Ab-2; GM-Tg-rg-MP0352-Ab-1/ GM-Tg-rg-MP0352-Ab-2;
GM-Tg-mg-MP0352-Ab-1/ GM-Tg-mg-MP0352-Ab-2; GM-Tg-cynog-MP0352-Ab-1/ GM-Tg-cynog-MP0352-Ab-2;
GM-Tg-felg-MP0352-Ab-1/ GM-Tg-felg-MP0352-Ab-2; GM-Tg-cang-MP0352-Ab-1/ GM-Tg-cang-MP0352-Ab-2;
GM-Tg-bovg-MP0352-Ab-1/ GM-Tg-bovg-MP0352-Ab-2; GM-Tg-equg-MP0352-Ab-1/ GM-Tg-equg-MP0352-Ab-2
Products NameAnti-DCSTAMP monoclonal antibody
Formatmab
Target NameDCSTAMP
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DCSTAMP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species DCSTP/ DCSTAMP/ FIND VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0352
    Target NameDCSTAMP
    Gene ID81501,75766,103690326,695237,100684603,101081191,512133,100062879
    Gene Symbol and Synonyms4833414I07Rik,DC-STAMP,DCSTAMP,FIND,hDC-STAMP,mDC-STAMP,™7SF4
    Uniprot AccessionQ9H295
    Uniprot Entry NameDCSTP_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164935
    Target ClassificationN/A

    The target: DCSTAMP, gene name: DCSTAMP, also named as FIND, ™7SF4, hDC-STAMP. This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.