Anti-DISP2/ C15orf36/ DISPB monoclonal antibody

Anti-DISP2/ C15orf36/ DISPB antibody for FACS & in-vivo assay

Target products collectionGo to DISP2/DISP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0362-Ab-1/ GM-Tg-hg-MP0362-Ab-2Anti-Human DISP2 monoclonal antibodyHuman
GM-Tg-rg-MP0362-Ab-1/ GM-Tg-rg-MP0362-Ab-2Anti-Rat DISP2 monoclonal antibodyRat
GM-Tg-mg-MP0362-Ab-1/ GM-Tg-mg-MP0362-Ab-2Anti-Mouse DISP2 monoclonal antibodyMouse
GM-Tg-cynog-MP0362-Ab-1/ GM-Tg-cynog-MP0362-Ab-2Anti-Cynomolgus/ Rhesus macaque DISP2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0362-Ab-1/ GM-Tg-felg-MP0362-Ab-2Anti-Feline DISP2 monoclonal antibodyFeline
GM-Tg-cang-MP0362-Ab-1/ GM-Tg-cang-MP0362-Ab-2Anti-Canine DISP2 monoclonal antibodyCanine
GM-Tg-bovg-MP0362-Ab-1/ GM-Tg-bovg-MP0362-Ab-2Anti-Bovine DISP2 monoclonal antibodyBovine
GM-Tg-equg-MP0362-Ab-1/ GM-Tg-equg-MP0362-Ab-2Anti-Equine DISP2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0362-Ab-1/ GM-Tg-hg-MP0362-Ab-2; GM-Tg-rg-MP0362-Ab-1/ GM-Tg-rg-MP0362-Ab-2;
GM-Tg-mg-MP0362-Ab-1/ GM-Tg-mg-MP0362-Ab-2; GM-Tg-cynog-MP0362-Ab-1/ GM-Tg-cynog-MP0362-Ab-2;
GM-Tg-felg-MP0362-Ab-1/ GM-Tg-felg-MP0362-Ab-2; GM-Tg-cang-MP0362-Ab-1/ GM-Tg-cang-MP0362-Ab-2;
GM-Tg-bovg-MP0362-Ab-1/ GM-Tg-bovg-MP0362-Ab-2; GM-Tg-equg-MP0362-Ab-1/ GM-Tg-equg-MP0362-Ab-2
Products NameAnti-DISP2 monoclonal antibody
Formatmab
Target NameDISP2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DISP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species DISP2/ C15orf36/ DISPB VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0362
    Target NameDISP2
    Gene ID85455,214240,311324,707523,100856240,101090441,512474,100071435
    Gene Symbol and SynonymsB230210L08Rik,C15orf36,DISP2,DISPB,HsT16908,LINC00594,mKIAA1742
    Uniprot AccessionA7MBM2
    Uniprot Entry NameDISP2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000140323
    Target ClassificationN/A

    The target: DISP2, gene name: DISP2, also named as C15orf36, DISPB, HsT16908, LINC00594. This gene is one of two human homologs of a segment-polarity gene known as dispatched identified in Drosophila. The product of this gene may be required for normal Hedgehog (Hh) signaling during embryonic pattern formation. [provided by RefSeq, Jan 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.