Anti-DJC13/ DNAJC13/ PARK21 monoclonal antibody

Anti-DJC13/ DNAJC13/ PARK21 antibody for FACS & in-vivo assay

Target products collectionGo to DNAJC13/DNAJC13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0365-Ab-1/ GM-Tg-hg-MP0365-Ab-2Anti-Human DNAJC13 monoclonal antibodyHuman
GM-Tg-rg-MP0365-Ab-1/ GM-Tg-rg-MP0365-Ab-2Anti-Rat DNAJC13 monoclonal antibodyRat
GM-Tg-mg-MP0365-Ab-1/ GM-Tg-mg-MP0365-Ab-2Anti-Mouse DNAJC13 monoclonal antibodyMouse
GM-Tg-cynog-MP0365-Ab-1/ GM-Tg-cynog-MP0365-Ab-2Anti-Cynomolgus/ Rhesus macaque DNAJC13 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0365-Ab-1/ GM-Tg-felg-MP0365-Ab-2Anti-Feline DNAJC13 monoclonal antibodyFeline
GM-Tg-cang-MP0365-Ab-1/ GM-Tg-cang-MP0365-Ab-2Anti-Canine DNAJC13 monoclonal antibodyCanine
GM-Tg-bovg-MP0365-Ab-1/ GM-Tg-bovg-MP0365-Ab-2Anti-Bovine DNAJC13 monoclonal antibodyBovine
GM-Tg-equg-MP0365-Ab-1/ GM-Tg-equg-MP0365-Ab-2Anti-Equine DNAJC13 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0365-Ab-1/ GM-Tg-hg-MP0365-Ab-2; GM-Tg-rg-MP0365-Ab-1/ GM-Tg-rg-MP0365-Ab-2;
GM-Tg-mg-MP0365-Ab-1/ GM-Tg-mg-MP0365-Ab-2; GM-Tg-cynog-MP0365-Ab-1/ GM-Tg-cynog-MP0365-Ab-2;
GM-Tg-felg-MP0365-Ab-1/ GM-Tg-felg-MP0365-Ab-2; GM-Tg-cang-MP0365-Ab-1/ GM-Tg-cang-MP0365-Ab-2;
GM-Tg-bovg-MP0365-Ab-1/ GM-Tg-bovg-MP0365-Ab-2; GM-Tg-equg-MP0365-Ab-1/ GM-Tg-equg-MP0365-Ab-2
Products NameAnti-DNAJC13 monoclonal antibody
Formatmab
Target NameDNAJC13
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DNAJC13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species DJC13/ DNAJC13/ PARK21 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0365
    Target NameDNAJC13
    Gene ID23317,235567,363127,717741,485663,101089388,504472,100052859
    Gene Symbol and SynonymsD030002L11Rik,DNAJC13,Gm1124,mKIAA0678,PARK21,RME-8,RME8
    Uniprot AccessionO75165
    Uniprot Entry NameDJC13_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000138246
    Target ClassificationN/A

    The target: DNAJC13, gene name: DNAJC13, also named as PARK21, RME8. This gene encodes a member of the Dnaj protein family whose members act as co-chaperones of a partner heat-shock protein by binding to the latter and stimulating ATP hydrolysis. The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis. It may also be involved in post-endocytic transport mechanisms via its associations with other proteins, including the sorting nexin SNX1. Mutations in this gene are associated with Parkinson's disease. [provided by RefSeq, Jun 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.