Anti-MUCL3/ C6orf37/ DPCR1 monoclonal antibody

Anti-MUCL3/ C6orf37/ DPCR1 antibody for FACS & in-vivo assay

Target products collectionGo to MUCL3/MUCL3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0369-Ab-1/ GM-Tg-hg-MP0369-Ab-2Anti-Human MUCL3 monoclonal antibodyHuman
GM-Tg-rg-MP0369-Ab-1/ GM-Tg-rg-MP0369-Ab-2Anti-Rat MUCL3 monoclonal antibodyRat
GM-Tg-mg-MP0369-Ab-1/ GM-Tg-mg-MP0369-Ab-2Anti-Mouse MUCL3 monoclonal antibodyMouse
GM-Tg-cynog-MP0369-Ab-1/ GM-Tg-cynog-MP0369-Ab-2Anti-Cynomolgus/ Rhesus macaque MUCL3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0369-Ab-1/ GM-Tg-felg-MP0369-Ab-2Anti-Feline MUCL3 monoclonal antibodyFeline
GM-Tg-cang-MP0369-Ab-1/ GM-Tg-cang-MP0369-Ab-2Anti-Canine MUCL3 monoclonal antibodyCanine
GM-Tg-bovg-MP0369-Ab-1/ GM-Tg-bovg-MP0369-Ab-2Anti-Bovine MUCL3 monoclonal antibodyBovine
GM-Tg-equg-MP0369-Ab-1/ GM-Tg-equg-MP0369-Ab-2Anti-Equine MUCL3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0369-Ab-1/ GM-Tg-hg-MP0369-Ab-2; GM-Tg-rg-MP0369-Ab-1/ GM-Tg-rg-MP0369-Ab-2;
GM-Tg-mg-MP0369-Ab-1/ GM-Tg-mg-MP0369-Ab-2; GM-Tg-cynog-MP0369-Ab-1/ GM-Tg-cynog-MP0369-Ab-2;
GM-Tg-felg-MP0369-Ab-1/ GM-Tg-felg-MP0369-Ab-2; GM-Tg-cang-MP0369-Ab-1/ GM-Tg-cang-MP0369-Ab-2;
GM-Tg-bovg-MP0369-Ab-1/ GM-Tg-bovg-MP0369-Ab-2; GM-Tg-equg-MP0369-Ab-1/ GM-Tg-equg-MP0369-Ab-2
Products NameAnti-MUCL3 monoclonal antibody
Formatmab
Target NameMUCL3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MUCL3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MUCL3/ C6orf37/ DPCR1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0369
    Target NameMUCL3
    Gene ID135656,268949,406199,714446,102152456,101100720,101907628,100055268
    Gene Symbol and SynonymsC6orf37,DPCR1,Gm630,MUCL3,PBLT
    Uniprot AccessionQ3MIW9,Q6MG22
    Uniprot Entry NameMUCL3_HUMAN,MUCL3_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168631
    Target ClassificationN/A

    The target: MUCL3, gene name: MUCL3, also named as C6orf37, DPCR1, PBLT. Predicted to be located in cytoplasm and plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.