Anti-DPEP3/ MBD3 monoclonal antibody

Anti-DPEP3/ MBD3 antibody for FACS & in-vivo assay

Target products collectionGo to DPEP3/DPEP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0370-Ab-1/ GM-Tg-hg-MP0370-Ab-2Anti-Human DPEP3 monoclonal antibodyHuman
GM-Tg-rg-MP0370-Ab-1/ GM-Tg-rg-MP0370-Ab-2Anti-Rat DPEP3 monoclonal antibodyRat
GM-Tg-mg-MP0370-Ab-1/ GM-Tg-mg-MP0370-Ab-2Anti-Mouse DPEP3 monoclonal antibodyMouse
GM-Tg-cynog-MP0370-Ab-1/ GM-Tg-cynog-MP0370-Ab-2Anti-Cynomolgus/ Rhesus macaque DPEP3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0370-Ab-1/ GM-Tg-felg-MP0370-Ab-2Anti-Feline DPEP3 monoclonal antibodyFeline
GM-Tg-cang-MP0370-Ab-1/ GM-Tg-cang-MP0370-Ab-2Anti-Canine DPEP3 monoclonal antibodyCanine
GM-Tg-bovg-MP0370-Ab-1/ GM-Tg-bovg-MP0370-Ab-2Anti-Bovine DPEP3 monoclonal antibodyBovine
GM-Tg-equg-MP0370-Ab-1/ GM-Tg-equg-MP0370-Ab-2Anti-Equine DPEP3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0370-Ab-1/ GM-Tg-hg-MP0370-Ab-2; GM-Tg-rg-MP0370-Ab-1/ GM-Tg-rg-MP0370-Ab-2;
GM-Tg-mg-MP0370-Ab-1/ GM-Tg-mg-MP0370-Ab-2; GM-Tg-cynog-MP0370-Ab-1/ GM-Tg-cynog-MP0370-Ab-2;
GM-Tg-felg-MP0370-Ab-1/ GM-Tg-felg-MP0370-Ab-2; GM-Tg-cang-MP0370-Ab-1/ GM-Tg-cang-MP0370-Ab-2;
GM-Tg-bovg-MP0370-Ab-1/ GM-Tg-bovg-MP0370-Ab-2; GM-Tg-equg-MP0370-Ab-1/ GM-Tg-equg-MP0370-Ab-2
Products NameAnti-DPEP3 monoclonal antibody
Formatmab
Target NameDPEP3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DPEP3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    BiosimilarGMP-Bios-ab-547Pre-Made Tamrintamab biosimilar, Whole mAb ADC, Anti-DPEP3 Antibody: Anti-MBD3 therapeutic antibody
    BiosimilarGMP-Bios-INN-1006Pre-Made Tamrintamab Pamozirine Biosimilar, Whole Mab Adc, Anti-Dpep3 Antibody: Anti-MBD3 therapeutic antibody Drug Conjugate
    Target AntigenProducts DevelopingMulti-species DPEP3/ MBD3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0370
    Target NameDPEP3
    Gene ID64180,71854,701327,101091327,100066409
    Gene Symbol and Synonyms1700018F16Rik,DPEP3,MBD-3,MBD3,MLZ-136
    Uniprot AccessionQ9H4B8
    Uniprot Entry NameDPEP3_HUMAN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, INN Index
    DiseaseN/A
    Gene EnsemblENSG00000141096
    Target ClassificationN/A

    The target: DPEP3, gene name: DPEP3, also named as MBD3. This gene encodes a membrane-bound glycoprotein from the family of dipeptidases involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family. Alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.