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Anti-DPP6/ DPL1/ DPPX monoclonal antibody
Anti-DPP6/ DPL1/ DPPX antibody for FACS & in-vivo assay
Go to DPP6/DPP6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0371-Ab-1/ GM-Tg-hg-MP0371-Ab-2 | Anti-Human DPP6 monoclonal antibody | Human |
| GM-Tg-rg-MP0371-Ab-1/ GM-Tg-rg-MP0371-Ab-2 | Anti-Rat DPP6 monoclonal antibody | Rat |
| GM-Tg-mg-MP0371-Ab-1/ GM-Tg-mg-MP0371-Ab-2 | Anti-Mouse DPP6 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0371-Ab-1/ GM-Tg-cynog-MP0371-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DPP6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0371-Ab-1/ GM-Tg-felg-MP0371-Ab-2 | Anti-Feline DPP6 monoclonal antibody | Feline |
| GM-Tg-cang-MP0371-Ab-1/ GM-Tg-cang-MP0371-Ab-2 | Anti-Canine DPP6 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0371-Ab-1/ GM-Tg-bovg-MP0371-Ab-2 | Anti-Bovine DPP6 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0371-Ab-1/ GM-Tg-equg-MP0371-Ab-2 | Anti-Equine DPP6 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0371-Ab-1/ GM-Tg-hg-MP0371-Ab-2; GM-Tg-rg-MP0371-Ab-1/ GM-Tg-rg-MP0371-Ab-2; GM-Tg-mg-MP0371-Ab-1/ GM-Tg-mg-MP0371-Ab-2; GM-Tg-cynog-MP0371-Ab-1/ GM-Tg-cynog-MP0371-Ab-2; GM-Tg-felg-MP0371-Ab-1/ GM-Tg-felg-MP0371-Ab-2; GM-Tg-cang-MP0371-Ab-1/ GM-Tg-cang-MP0371-Ab-2; GM-Tg-bovg-MP0371-Ab-1/ GM-Tg-bovg-MP0371-Ab-2; GM-Tg-equg-MP0371-Ab-1/ GM-Tg-equg-MP0371-Ab-2 |
| Products Name | Anti-DPP6 monoclonal antibody |
| Format | mab |
| Target Name | DPP6 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DPP6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species DPP6/ DPL1/ DPPX VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0371 |
| Target Name | DPP6 |
| Gene ID | 1804,13483,29272,718148,475553,101084350,281123,100063666 |
| Gene Symbol and Synonyms | B930011P16Rik,D5Buc3,D5Buc4,D5Buc5,DPL1,DPP VI,Dpp-6,DPP6,DPPX,Gm1377,In(5)6H-p,MRD33,Peplb,Rw,VF2 |
| Uniprot Accession | P42658,P46101,P42659 |
| Uniprot Entry Name | DPP6_HUMAN,DPP6_RAT,DPP6_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000130226 |
| Target Classification | N/A |
The target: DPP6, gene name: DPP6, also named as DPL1, DPPX, MRD33, VF2. This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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