Anti-DSCL1/ DSCAML1/ DSCAM2 monoclonal antibody

Anti-DSCL1/ DSCAML1/ DSCAM2 antibody for FACS & in-vivo assay

Target products collectionGo to DSCAML1/DSCAML1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0377-Ab-1/ GM-Tg-hg-MP0377-Ab-2Anti-Human DSCAML1 monoclonal antibodyHuman
GM-Tg-rg-MP0377-Ab-1/ GM-Tg-rg-MP0377-Ab-2Anti-Rat DSCAML1 monoclonal antibodyRat
GM-Tg-mg-MP0377-Ab-1/ GM-Tg-mg-MP0377-Ab-2Anti-Mouse DSCAML1 monoclonal antibodyMouse
GM-Tg-cynog-MP0377-Ab-1/ GM-Tg-cynog-MP0377-Ab-2Anti-Cynomolgus/ Rhesus macaque DSCAML1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0377-Ab-1/ GM-Tg-felg-MP0377-Ab-2Anti-Feline DSCAML1 monoclonal antibodyFeline
GM-Tg-cang-MP0377-Ab-1/ GM-Tg-cang-MP0377-Ab-2Anti-Canine DSCAML1 monoclonal antibodyCanine
GM-Tg-bovg-MP0377-Ab-1/ GM-Tg-bovg-MP0377-Ab-2Anti-Bovine DSCAML1 monoclonal antibodyBovine
GM-Tg-equg-MP0377-Ab-1/ GM-Tg-equg-MP0377-Ab-2Anti-Equine DSCAML1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0377-Ab-1/ GM-Tg-hg-MP0377-Ab-2; GM-Tg-rg-MP0377-Ab-1/ GM-Tg-rg-MP0377-Ab-2;
GM-Tg-mg-MP0377-Ab-1/ GM-Tg-mg-MP0377-Ab-2; GM-Tg-cynog-MP0377-Ab-1/ GM-Tg-cynog-MP0377-Ab-2;
GM-Tg-felg-MP0377-Ab-1/ GM-Tg-felg-MP0377-Ab-2; GM-Tg-cang-MP0377-Ab-1/ GM-Tg-cang-MP0377-Ab-2;
GM-Tg-bovg-MP0377-Ab-1/ GM-Tg-bovg-MP0377-Ab-2; GM-Tg-equg-MP0377-Ab-1/ GM-Tg-equg-MP0377-Ab-2
Products NameAnti-DSCAML1 monoclonal antibody
Formatmab
Target NameDSCAML1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DSCAML1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species DSCL1/ DSCAML1/ DSCAM2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0377
    Target NameDSCAML1
    Gene ID57453,114873,315615,698212,489388,101082341,538739,102149147
    Gene Symbol and Synonyms4921507G06Rik,4930435C18Rik,DSCAM2,DSCAML1,mKIAA1132
    Uniprot AccessionQ8TD84
    Uniprot Entry NameDSCL1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000177103
    Target ClassificationN/A

    The target: DSCAML1, gene name: DSCAML1, also named as DSCAM2. The protein encoded by this gene is a member of the Ig superfamily of cell adhesion molecules and is involved in neuronal differentiation. The encoded membrane-bound protein localizes to the cell surface, where it forms aggregates that repel neuronal processes of the same cell type. [provided by RefSeq, Sep 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.