- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-DTNA/ D18S892E/ DRP3 monoclonal antibody
Anti-DTNA/ D18S892E/ DRP3 antibody for FACS & in-vivo assay
Go to DTNA/DTNA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0381-Ab-1/ GM-Tg-hg-MP0381-Ab-2 | Anti-Human DTNA monoclonal antibody | Human |
| GM-Tg-rg-MP0381-Ab-1/ GM-Tg-rg-MP0381-Ab-2 | Anti-Rat DTNA monoclonal antibody | Rat |
| GM-Tg-mg-MP0381-Ab-1/ GM-Tg-mg-MP0381-Ab-2 | Anti-Mouse DTNA monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0381-Ab-1/ GM-Tg-cynog-MP0381-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DTNA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0381-Ab-1/ GM-Tg-felg-MP0381-Ab-2 | Anti-Feline DTNA monoclonal antibody | Feline |
| GM-Tg-cang-MP0381-Ab-1/ GM-Tg-cang-MP0381-Ab-2 | Anti-Canine DTNA monoclonal antibody | Canine |
| GM-Tg-bovg-MP0381-Ab-1/ GM-Tg-bovg-MP0381-Ab-2 | Anti-Bovine DTNA monoclonal antibody | Bovine |
| GM-Tg-equg-MP0381-Ab-1/ GM-Tg-equg-MP0381-Ab-2 | Anti-Equine DTNA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0381-Ab-1/ GM-Tg-hg-MP0381-Ab-2; GM-Tg-rg-MP0381-Ab-1/ GM-Tg-rg-MP0381-Ab-2; GM-Tg-mg-MP0381-Ab-1/ GM-Tg-mg-MP0381-Ab-2; GM-Tg-cynog-MP0381-Ab-1/ GM-Tg-cynog-MP0381-Ab-2; GM-Tg-felg-MP0381-Ab-1/ GM-Tg-felg-MP0381-Ab-2; GM-Tg-cang-MP0381-Ab-1/ GM-Tg-cang-MP0381-Ab-2; GM-Tg-bovg-MP0381-Ab-1/ GM-Tg-bovg-MP0381-Ab-2; GM-Tg-equg-MP0381-Ab-1/ GM-Tg-equg-MP0381-Ab-2 |
| Products Name | Anti-DTNA monoclonal antibody |
| Format | mab |
| Target Name | DTNA |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DTNA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species DTNA/ D18S892E/ DRP3 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0381 |
| Target Name | DTNA |
| Gene ID | 1837,13527,307548,707887,490488,101090394,541153,100052566 |
| Gene Symbol and Synonyms | 2210407P21Rik,a-DB-1,adbn,D18S892E,DRP3,DTN,DTN-A,DTNA,Dtna-ps1,Gm19389,LVNC1,RGD1561985 |
| Uniprot Accession | Q9Y4J8 |
| Uniprot Entry Name | DTNA_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000134769 |
| Target Classification | N/A |
The target: DTNA, gene name: DTNA, also named as D18S892E, DRP3, DTN, DTN-A, LVNC1. The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
