- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-EFNA2/ ELF-1/ EPLG6 monoclonal antibody
Anti-EFNA2/ ELF-1/ EPLG6 antibody for FACS & in-vivo assay
Go to EFNA2/EFNA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0393-Ab-1/ GM-Tg-hg-MP0393-Ab-2 | Anti-Human EFNA2 monoclonal antibody | Human |
| GM-Tg-rg-MP0393-Ab-1/ GM-Tg-rg-MP0393-Ab-2 | Anti-Rat EFNA2 monoclonal antibody | Rat |
| GM-Tg-mg-MP0393-Ab-1/ GM-Tg-mg-MP0393-Ab-2 | Anti-Mouse EFNA2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0393-Ab-1/ GM-Tg-cynog-MP0393-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EFNA2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0393-Ab-1/ GM-Tg-felg-MP0393-Ab-2 | Anti-Feline EFNA2 monoclonal antibody | Feline |
| GM-Tg-cang-MP0393-Ab-1/ GM-Tg-cang-MP0393-Ab-2 | Anti-Canine EFNA2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0393-Ab-1/ GM-Tg-bovg-MP0393-Ab-2 | Anti-Bovine EFNA2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0393-Ab-1/ GM-Tg-equg-MP0393-Ab-2 | Anti-Equine EFNA2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0393-Ab-1/ GM-Tg-hg-MP0393-Ab-2; GM-Tg-rg-MP0393-Ab-1/ GM-Tg-rg-MP0393-Ab-2; GM-Tg-mg-MP0393-Ab-1/ GM-Tg-mg-MP0393-Ab-2; GM-Tg-cynog-MP0393-Ab-1/ GM-Tg-cynog-MP0393-Ab-2; GM-Tg-felg-MP0393-Ab-1/ GM-Tg-felg-MP0393-Ab-2; GM-Tg-cang-MP0393-Ab-1/ GM-Tg-cang-MP0393-Ab-2; GM-Tg-bovg-MP0393-Ab-1/ GM-Tg-bovg-MP0393-Ab-2; GM-Tg-equg-MP0393-Ab-1/ GM-Tg-equg-MP0393-Ab-2 |
| Products Name | Anti-EFNA2 monoclonal antibody |
| Format | mab |
| Target Name | EFNA2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-EFNA2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species EFNA2/ ELF-1/ EPLG6 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP004638 | human EFNA2 Lentivirus particle |
| ORF Viral Vector | pGMLP004638 | human EFNA2 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003747 | mouse Efna2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003747 | mouse Efna2 Lentivirus particle |
Target information
| Target ID | GM-MP0393 |
| Target Name | EFNA2 |
| Gene ID | 1943,13637,84358,721231,119864601,111557556,614453,111774429 |
| Gene Symbol and Synonyms | CEK7L,EFNA2,ELF-1,Elf1,Epl6,EPLG6,HEK7-L,LERK-6,LERK6 |
| Uniprot Accession | O43921 |
| Uniprot Entry Name | EFNA2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000099617 |
| Target Classification | N/A |
The target: EFNA2, gene name: EFNA2, also named as ELF-1, EPLG6, HEK7-L, LERK-6, LERK6. This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
