Anti-MUCEN/ EMCN/ EMCN2 monoclonal antibody

Anti-MUCEN/ EMCN/ EMCN2 antibody for FACS & in-vivo assay

Target products collectionGo to EMCN/EMCN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0402-Ab-1/ GM-Tg-hg-MP0402-Ab-2Anti-Human EMCN monoclonal antibodyHuman
GM-Tg-rg-MP0402-Ab-1/ GM-Tg-rg-MP0402-Ab-2Anti-Rat EMCN monoclonal antibodyRat
GM-Tg-mg-MP0402-Ab-1/ GM-Tg-mg-MP0402-Ab-2Anti-Mouse EMCN monoclonal antibodyMouse
GM-Tg-cynog-MP0402-Ab-1/ GM-Tg-cynog-MP0402-Ab-2Anti-Cynomolgus/ Rhesus macaque EMCN monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0402-Ab-1/ GM-Tg-felg-MP0402-Ab-2Anti-Feline EMCN monoclonal antibodyFeline
GM-Tg-cang-MP0402-Ab-1/ GM-Tg-cang-MP0402-Ab-2Anti-Canine EMCN monoclonal antibodyCanine
GM-Tg-bovg-MP0402-Ab-1/ GM-Tg-bovg-MP0402-Ab-2Anti-Bovine EMCN monoclonal antibodyBovine
GM-Tg-equg-MP0402-Ab-1/ GM-Tg-equg-MP0402-Ab-2Anti-Equine EMCN monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0402-Ab-1/ GM-Tg-hg-MP0402-Ab-2; GM-Tg-rg-MP0402-Ab-1/ GM-Tg-rg-MP0402-Ab-2;
GM-Tg-mg-MP0402-Ab-1/ GM-Tg-mg-MP0402-Ab-2; GM-Tg-cynog-MP0402-Ab-1/ GM-Tg-cynog-MP0402-Ab-2;
GM-Tg-felg-MP0402-Ab-1/ GM-Tg-felg-MP0402-Ab-2; GM-Tg-cang-MP0402-Ab-1/ GM-Tg-cang-MP0402-Ab-2;
GM-Tg-bovg-MP0402-Ab-1/ GM-Tg-bovg-MP0402-Ab-2; GM-Tg-equg-MP0402-Ab-1/ GM-Tg-equg-MP0402-Ab-2
Products NameAnti-EMCN monoclonal antibody
Formatmab
Target NameEMCN
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EMCN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MUCEN/ EMCN/ EMCN2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0402
    Target NameEMCN
    Gene ID51705,59308,295490,709580,609940,101097891,616367,102150017
    Gene Symbol and Synonyms0610012K22Rik,EMCN,EMCN2,MUC14
    Uniprot AccessionQ9ULC0,Q6AY82
    Uniprot Entry NameMUCEN_HUMAN,MUCEN_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164035
    Target ClassificationN/A

    The target: EMCN, gene name: EMCN, also named as EMCN2, MUC14. EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.