Anti-ENOA/ ENO1/ ENO1L1 monoclonal antibody

Anti-ENOA/ ENO1/ ENO1L1 antibody for FACS & in-vivo assay

Target products collectionGo to ENO1/ENO1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0408-Ab-1/ GM-Tg-hg-MP0408-Ab-2Anti-Human ENO1 monoclonal antibodyHuman
GM-Tg-rg-MP0408-Ab-1/ GM-Tg-rg-MP0408-Ab-2Anti-Rat ENO1 monoclonal antibodyRat
GM-Tg-mg-MP0408-Ab-1/ GM-Tg-mg-MP0408-Ab-2Anti-Mouse ENO1 monoclonal antibodyMouse
GM-Tg-cynog-MP0408-Ab-1/ GM-Tg-cynog-MP0408-Ab-2Anti-Cynomolgus/ Rhesus macaque ENO1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0408-Ab-1/ GM-Tg-felg-MP0408-Ab-2Anti-Feline ENO1 monoclonal antibodyFeline
GM-Tg-cang-MP0408-Ab-1/ GM-Tg-cang-MP0408-Ab-2Anti-Canine ENO1 monoclonal antibodyCanine
GM-Tg-bovg-MP0408-Ab-1/ GM-Tg-bovg-MP0408-Ab-2Anti-Bovine ENO1 monoclonal antibodyBovine
GM-Tg-equg-MP0408-Ab-1/ GM-Tg-equg-MP0408-Ab-2Anti-Equine ENO1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0408-Ab-1/ GM-Tg-hg-MP0408-Ab-2; GM-Tg-rg-MP0408-Ab-1/ GM-Tg-rg-MP0408-Ab-2;
GM-Tg-mg-MP0408-Ab-1/ GM-Tg-mg-MP0408-Ab-2; GM-Tg-cynog-MP0408-Ab-1/ GM-Tg-cynog-MP0408-Ab-2;
GM-Tg-felg-MP0408-Ab-1/ GM-Tg-felg-MP0408-Ab-2; GM-Tg-cang-MP0408-Ab-1/ GM-Tg-cang-MP0408-Ab-2;
GM-Tg-bovg-MP0408-Ab-1/ GM-Tg-bovg-MP0408-Ab-2; GM-Tg-equg-MP0408-Ab-1/ GM-Tg-equg-MP0408-Ab-2
Products NameAnti-ENO1 monoclonal antibody
Formatmab
Target NameENO1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ENO1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ENOA/ ENO1/ ENO1L1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP002092human ENO1 Lentivirus plasmid
    ORF Viral VectorvGMLP002092human ENO1 Lentivirus particle
    ORF Viral VectorpGMLPm005190mouse Eno1 Lentivirus plasmid
    ORF Viral VectorpGMLPm005326mouse Eno1 Lentivirus plasmid
    ORF Viral VectorvGMLPm005190mouse Eno1 Lentivirus particle
    ORF Viral VectorvGMLPm005326mouse Eno1 Lentivirus particle


    Target information

    Target IDGM-MP0408
    Target NameENO1
    Gene ID2023,13806,24333,709378,479597,101093622,281141,100051879
    Gene Symbol and SynonymsEno-1,ENO1,ENO1-IT1,ENO1L1,HEL-S-17,MBP-1,MPB1,NNE,PPH
    Uniprot AccessionP06733,P04764,Q9XSJ4
    Uniprot Entry NameENOA_HUMAN,ENOA_RAT,ENOA_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseDent disease
    Gene EnsemblENSG00000074800
    Target ClassificationN/A

    The target: ENO1, gene name: ENO1, also named as ENO1L1, HEL-S-17, MPB1, NNE, PPH. This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.