Anti-ENPP6/ NPP6 monoclonal antibody

Anti-ENPP6/ NPP6 antibody for FACS & in-vivo assay

Target products collectionGo to ENPP6/ENPP6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0412-Ab-1/ GM-Tg-hg-MP0412-Ab-2Anti-Human ENPP6 monoclonal antibodyHuman
GM-Tg-rg-MP0412-Ab-1/ GM-Tg-rg-MP0412-Ab-2Anti-Rat ENPP6 monoclonal antibodyRat
GM-Tg-mg-MP0412-Ab-1/ GM-Tg-mg-MP0412-Ab-2Anti-Mouse ENPP6 monoclonal antibodyMouse
GM-Tg-cynog-MP0412-Ab-1/ GM-Tg-cynog-MP0412-Ab-2Anti-Cynomolgus/ Rhesus macaque ENPP6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0412-Ab-1/ GM-Tg-felg-MP0412-Ab-2Anti-Feline ENPP6 monoclonal antibodyFeline
GM-Tg-cang-MP0412-Ab-1/ GM-Tg-cang-MP0412-Ab-2Anti-Canine ENPP6 monoclonal antibodyCanine
GM-Tg-bovg-MP0412-Ab-1/ GM-Tg-bovg-MP0412-Ab-2Anti-Bovine ENPP6 monoclonal antibodyBovine
GM-Tg-equg-MP0412-Ab-1/ GM-Tg-equg-MP0412-Ab-2Anti-Equine ENPP6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0412-Ab-1/ GM-Tg-hg-MP0412-Ab-2; GM-Tg-rg-MP0412-Ab-1/ GM-Tg-rg-MP0412-Ab-2;
GM-Tg-mg-MP0412-Ab-1/ GM-Tg-mg-MP0412-Ab-2; GM-Tg-cynog-MP0412-Ab-1/ GM-Tg-cynog-MP0412-Ab-2;
GM-Tg-felg-MP0412-Ab-1/ GM-Tg-felg-MP0412-Ab-2; GM-Tg-cang-MP0412-Ab-1/ GM-Tg-cang-MP0412-Ab-2;
GM-Tg-bovg-MP0412-Ab-1/ GM-Tg-bovg-MP0412-Ab-2; GM-Tg-equg-MP0412-Ab-1/ GM-Tg-equg-MP0412-Ab-2
Products NameAnti-ENPP6 monoclonal antibody
Formatmab
Target NameENPP6
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ENPP6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ENPP6/ NPP6 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0412
    Target NameENPP6
    Gene ID133121,320981,306460,693950,475636,101089347,537431,100058368
    Gene Symbol and Synonyms4833421B01Rik,B830047L21Rik,D8Ertd514e,E-NPP 6,ENPP6,GPC-Cpde,NPP-6,NPP6
    Uniprot AccessionQ6UWR7,B0BND0,F1N5C8
    Uniprot Entry NameENPP6_HUMAN,ENPP6_RAT,ENPP6_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164303
    Target ClassificationN/A

    The target: ENPP6, gene name: ENPP6, also named as NPP6. Enables glycerophosphocholine cholinephosphodiesterase activity. Involved in choline metabolic process and lipid metabolic process. Located in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.