Anti-ENTP6/ ENTPD6/ CD39L2 monoclonal antibody

Anti-ENTP6/ ENTPD6/ CD39L2 antibody for FACS & in-vivo assay

Target products collectionGo to ENTPD6/ENTPD6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0416-Ab-1/ GM-Tg-hg-MP0416-Ab-2Anti-Human ENTPD6 monoclonal antibodyHuman
GM-Tg-rg-MP0416-Ab-1/ GM-Tg-rg-MP0416-Ab-2Anti-Rat ENTPD6 monoclonal antibodyRat
GM-Tg-mg-MP0416-Ab-1/ GM-Tg-mg-MP0416-Ab-2Anti-Mouse ENTPD6 monoclonal antibodyMouse
GM-Tg-cynog-MP0416-Ab-1/ GM-Tg-cynog-MP0416-Ab-2Anti-Cynomolgus/ Rhesus macaque ENTPD6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0416-Ab-1/ GM-Tg-felg-MP0416-Ab-2Anti-Feline ENTPD6 monoclonal antibodyFeline
GM-Tg-cang-MP0416-Ab-1/ GM-Tg-cang-MP0416-Ab-2Anti-Canine ENTPD6 monoclonal antibodyCanine
GM-Tg-bovg-MP0416-Ab-1/ GM-Tg-bovg-MP0416-Ab-2Anti-Bovine ENTPD6 monoclonal antibodyBovine
GM-Tg-equg-MP0416-Ab-1/ GM-Tg-equg-MP0416-Ab-2Anti-Equine ENTPD6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0416-Ab-1/ GM-Tg-hg-MP0416-Ab-2; GM-Tg-rg-MP0416-Ab-1/ GM-Tg-rg-MP0416-Ab-2;
GM-Tg-mg-MP0416-Ab-1/ GM-Tg-mg-MP0416-Ab-2; GM-Tg-cynog-MP0416-Ab-1/ GM-Tg-cynog-MP0416-Ab-2;
GM-Tg-felg-MP0416-Ab-1/ GM-Tg-felg-MP0416-Ab-2; GM-Tg-cang-MP0416-Ab-1/ GM-Tg-cang-MP0416-Ab-2;
GM-Tg-bovg-MP0416-Ab-1/ GM-Tg-bovg-MP0416-Ab-2; GM-Tg-equg-MP0416-Ab-1/ GM-Tg-equg-MP0416-Ab-2
Products NameAnti-ENTPD6 monoclonal antibody
Formatmab
Target NameENTPD6
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ENTPD6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ENTP6/ ENTPD6/ CD39L2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0416
    Target NameENTPD6
    Gene ID955,12497,85260,705663,485564,101090852,508097,100057043
    Gene Symbol and Synonyms2700026H11Rik,CD39L2,dJ738P15.3,ENTPD6,IL-6SAG,IL6ST2,NTPDase-6
    Uniprot AccessionO75354,Q9ER31
    Uniprot Entry NameENTP6_HUMAN,ENTP6_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000197586
    Target ClassificationN/A

    The target: ENTPD6, gene name: ENTPD6, also named as CD39L2, IL-6SAG, IL6ST2, NTPDase-6, dJ738P15.3. ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which are characteristic of NTPases. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.