Anti-E41L3/ EPB41L3/ 4.1B monoclonal antibody

Anti-E41L3/ EPB41L3/ 4.1B antibody for FACS & in-vivo assay

Target products collectionGo to EPB41L3/EPB41L3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0418-Ab-1/ GM-Tg-hg-MP0418-Ab-2Anti-Human EPB41L3 monoclonal antibodyHuman
GM-Tg-rg-MP0418-Ab-1/ GM-Tg-rg-MP0418-Ab-2Anti-Rat EPB41L3 monoclonal antibodyRat
GM-Tg-mg-MP0418-Ab-1/ GM-Tg-mg-MP0418-Ab-2Anti-Mouse EPB41L3 monoclonal antibodyMouse
GM-Tg-cynog-MP0418-Ab-1/ GM-Tg-cynog-MP0418-Ab-2Anti-Cynomolgus/ Rhesus macaque EPB41L3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0418-Ab-1/ GM-Tg-felg-MP0418-Ab-2Anti-Feline EPB41L3 monoclonal antibodyFeline
GM-Tg-cang-MP0418-Ab-1/ GM-Tg-cang-MP0418-Ab-2Anti-Canine EPB41L3 monoclonal antibodyCanine
GM-Tg-bovg-MP0418-Ab-1/ GM-Tg-bovg-MP0418-Ab-2Anti-Bovine EPB41L3 monoclonal antibodyBovine
GM-Tg-equg-MP0418-Ab-1/ GM-Tg-equg-MP0418-Ab-2Anti-Equine EPB41L3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0418-Ab-1/ GM-Tg-hg-MP0418-Ab-2; GM-Tg-rg-MP0418-Ab-1/ GM-Tg-rg-MP0418-Ab-2;
GM-Tg-mg-MP0418-Ab-1/ GM-Tg-mg-MP0418-Ab-2; GM-Tg-cynog-MP0418-Ab-1/ GM-Tg-cynog-MP0418-Ab-2;
GM-Tg-felg-MP0418-Ab-1/ GM-Tg-felg-MP0418-Ab-2; GM-Tg-cang-MP0418-Ab-1/ GM-Tg-cang-MP0418-Ab-2;
GM-Tg-bovg-MP0418-Ab-1/ GM-Tg-bovg-MP0418-Ab-2; GM-Tg-equg-MP0418-Ab-1/ GM-Tg-equg-MP0418-Ab-2
Products NameAnti-EPB41L3 monoclonal antibody
Formatmab
Target NameEPB41L3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EPB41L3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species E41L3/ EPB41L3/ 4.1B VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP003234human EPB41L3 Lentivirus particle
    ORF Viral VectorpGMLP003234human EPB41L3 Lentivirus plasmid


    Target information

    Target IDGM-MP0418
    Target NameEPB41L3
    Gene ID23136,13823,116724,693475,480198,101083805,532616,100059101
    Gene Symbol and Synonyms4.1B,DAL-1,DAL1,DAL1P,Epb4.1l3,EPB41L3,Kiaa0987,NBL3
    Uniprot AccessionQ9Y2J2
    Uniprot Entry NameE41L3_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseOvary Cancer
    Gene EnsemblENSG00000082397
    Target ClassificationN/A

    The target: EPB41L3, gene name: EPB41L3, also named as 4.1B, DAL-1, DAL1. Predicted to enable cytoskeletal protein-membrane anchor activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in several processes, including nervous system development; paranodal junction maintenance; and protein localization to paranode region of axon. Located in cell-cell junction and plasma membrane. Biomarker of meningioma. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.