Anti-EPHAA/ EPHA10 monoclonal antibody

Anti-EPHAA/ EPHA10 antibody for FACS & in-vivo assay

Target products collectionGo to EPHA10/EPHA10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0419-Ab-1/ GM-Tg-hg-MP0419-Ab-2Anti-Human EPHA10 monoclonal antibodyHuman
GM-Tg-rg-MP0419-Ab-1/ GM-Tg-rg-MP0419-Ab-2Anti-Rat EPHA10 monoclonal antibodyRat
GM-Tg-mg-MP0419-Ab-1/ GM-Tg-mg-MP0419-Ab-2Anti-Mouse EPHA10 monoclonal antibodyMouse
GM-Tg-cynog-MP0419-Ab-1/ GM-Tg-cynog-MP0419-Ab-2Anti-Cynomolgus/ Rhesus macaque EPHA10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0419-Ab-1/ GM-Tg-felg-MP0419-Ab-2Anti-Feline EPHA10 monoclonal antibodyFeline
GM-Tg-cang-MP0419-Ab-1/ GM-Tg-cang-MP0419-Ab-2Anti-Canine EPHA10 monoclonal antibodyCanine
GM-Tg-bovg-MP0419-Ab-1/ GM-Tg-bovg-MP0419-Ab-2Anti-Bovine EPHA10 monoclonal antibodyBovine
GM-Tg-equg-MP0419-Ab-1/ GM-Tg-equg-MP0419-Ab-2Anti-Equine EPHA10 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0419-Ab-1/ GM-Tg-hg-MP0419-Ab-2; GM-Tg-rg-MP0419-Ab-1/ GM-Tg-rg-MP0419-Ab-2;
GM-Tg-mg-MP0419-Ab-1/ GM-Tg-mg-MP0419-Ab-2; GM-Tg-cynog-MP0419-Ab-1/ GM-Tg-cynog-MP0419-Ab-2;
GM-Tg-felg-MP0419-Ab-1/ GM-Tg-felg-MP0419-Ab-2; GM-Tg-cang-MP0419-Ab-1/ GM-Tg-cang-MP0419-Ab-2;
GM-Tg-bovg-MP0419-Ab-1/ GM-Tg-bovg-MP0419-Ab-2; GM-Tg-equg-MP0419-Ab-1/ GM-Tg-equg-MP0419-Ab-2
Products NameAnti-EPHA10 monoclonal antibody
Formatmab
Target NameEPHA10
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EPHA10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species EPHAA/ EPHA10 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0419
    Target NameEPHA10
    Gene ID284656,230735,298528,100426059,482471,101091797,540439,100069107
    Gene Symbol and SynonymsA330090H18,DFNA88,EPHA10,RGD1562679
    Uniprot AccessionQ5JZY3
    Uniprot Entry NameEPHAA_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000183317
    Target ClassificationN/A

    The target: EPHA10, gene name: EPHA10, also named as . Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.