Anti-ESYT1/ FAM62A/ MBC2 monoclonal antibody

Anti-ESYT1/ FAM62A/ MBC2 antibody for FACS & in-vivo assay

Target products collectionGo to ESYT1/ESYT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0426-Ab-1/ GM-Tg-hg-MP0426-Ab-2Anti-Human ESYT1 monoclonal antibodyHuman
GM-Tg-rg-MP0426-Ab-1/ GM-Tg-rg-MP0426-Ab-2Anti-Rat ESYT1 monoclonal antibodyRat
GM-Tg-mg-MP0426-Ab-1/ GM-Tg-mg-MP0426-Ab-2Anti-Mouse ESYT1 monoclonal antibodyMouse
GM-Tg-cynog-MP0426-Ab-1/ GM-Tg-cynog-MP0426-Ab-2Anti-Cynomolgus/ Rhesus macaque ESYT1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0426-Ab-1/ GM-Tg-felg-MP0426-Ab-2Anti-Feline ESYT1 monoclonal antibodyFeline
GM-Tg-cang-MP0426-Ab-1/ GM-Tg-cang-MP0426-Ab-2Anti-Canine ESYT1 monoclonal antibodyCanine
GM-Tg-bovg-MP0426-Ab-1/ GM-Tg-bovg-MP0426-Ab-2Anti-Bovine ESYT1 monoclonal antibodyBovine
GM-Tg-equg-MP0426-Ab-1/ GM-Tg-equg-MP0426-Ab-2Anti-Equine ESYT1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0426-Ab-1/ GM-Tg-hg-MP0426-Ab-2; GM-Tg-rg-MP0426-Ab-1/ GM-Tg-rg-MP0426-Ab-2;
GM-Tg-mg-MP0426-Ab-1/ GM-Tg-mg-MP0426-Ab-2; GM-Tg-cynog-MP0426-Ab-1/ GM-Tg-cynog-MP0426-Ab-2;
GM-Tg-felg-MP0426-Ab-1/ GM-Tg-felg-MP0426-Ab-2; GM-Tg-cang-MP0426-Ab-1/ GM-Tg-cang-MP0426-Ab-2;
GM-Tg-bovg-MP0426-Ab-1/ GM-Tg-bovg-MP0426-Ab-2; GM-Tg-equg-MP0426-Ab-1/ GM-Tg-equg-MP0426-Ab-2
Products NameAnti-ESYT1 monoclonal antibody
Formatmab
Target NameESYT1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ESYT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ESYT1/ FAM62A/ MBC2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0426
    Target NameESYT1
    Gene ID23344,23943,29579,711720,474397,101095348,520669,100051975
    Gene Symbol and SynonymsESYT1,FAM62A,MBC2,vp115
    Uniprot AccessionQ9BSJ8,Q9Z1X1
    Uniprot Entry NameESYT1_HUMAN,ESYT1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000139641
    Target ClassificationN/A

    The target: ESYT1, gene name: ESYT1, also named as FAM62A, MBC2. Enables identical protein binding activity. Predicted to be involved in endoplasmic reticulum-plasma membrane tethering and lipid transport. Located in endoplasmic reticulum. Is integral component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.