Anti-FCGRB/ FCGR1B/ CD64b monoclonal antibody

Anti-FCGRB/ FCGR1B/ CD64b antibody for FACS & in-vivo assay

Target products collectionGo to FCGR1B/FCGR1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0439-Ab-1/ GM-Tg-hg-MP0439-Ab-2Anti-Human FCGR1B monoclonal antibodyHuman
GM-Tg-rg-MP0439-Ab-1/ GM-Tg-rg-MP0439-Ab-2Anti-Rat FCGR1B monoclonal antibodyRat
GM-Tg-mg-MP0439-Ab-1/ GM-Tg-mg-MP0439-Ab-2Anti-Mouse FCGR1B monoclonal antibodyMouse
GM-Tg-cynog-MP0439-Ab-1/ GM-Tg-cynog-MP0439-Ab-2Anti-Cynomolgus/ Rhesus macaque FCGR1B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0439-Ab-1/ GM-Tg-felg-MP0439-Ab-2Anti-Feline FCGR1B monoclonal antibodyFeline
GM-Tg-cang-MP0439-Ab-1/ GM-Tg-cang-MP0439-Ab-2Anti-Canine FCGR1B monoclonal antibodyCanine
GM-Tg-bovg-MP0439-Ab-1/ GM-Tg-bovg-MP0439-Ab-2Anti-Bovine FCGR1B monoclonal antibodyBovine
GM-Tg-equg-MP0439-Ab-1/ GM-Tg-equg-MP0439-Ab-2Anti-Equine FCGR1B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0439-Ab-1/ GM-Tg-hg-MP0439-Ab-2; GM-Tg-rg-MP0439-Ab-1/ GM-Tg-rg-MP0439-Ab-2;
GM-Tg-mg-MP0439-Ab-1/ GM-Tg-mg-MP0439-Ab-2; GM-Tg-cynog-MP0439-Ab-1/ GM-Tg-cynog-MP0439-Ab-2;
GM-Tg-felg-MP0439-Ab-1/ GM-Tg-felg-MP0439-Ab-2; GM-Tg-cang-MP0439-Ab-1/ GM-Tg-cang-MP0439-Ab-2;
GM-Tg-bovg-MP0439-Ab-1/ GM-Tg-bovg-MP0439-Ab-2; GM-Tg-equg-MP0439-Ab-1/ GM-Tg-equg-MP0439-Ab-2
Products NameAnti-FCGR1B monoclonal antibody
Formatmab
Target NameFCGR1B
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FCGR1B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species FCGRB/ FCGR1B/ CD64b VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0439
    Target NameFCGR1B
    Gene ID2210
    Gene Symbol and SynonymsCD34,CD64b,FCG1,FcgammaRIa,FCGR1,FCGR1B,FCGR1BP,FcRI,IGFR1,IGFRB
    Uniprot AccessionQ92637
    Uniprot Entry NameFCGRB_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000198019
    Target ClassificationN/A

    The target: FCGR1B, gene name: FCGR1B, also named as CD64b, FCG1, FCGR1, FCGR1A, FcRI, FcgammaRIa, IGFR1, IGFRB. Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene likely encodes a non-functional protein that is not detectable at the cell surface and binds ligand with low affinity. [provided by RefSeq, Nov 2019].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.