Anti-FCRL6/ FcRH6 monoclonal antibody

Anti-FCRL6/ FcRH6 antibody for FACS & in-vivo assay

Target products collectionGo to FCRL6/FCRL6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0440-Ab-1/ GM-Tg-hg-MP0440-Ab-2Anti-Human FCRL6 monoclonal antibodyHuman
GM-Tg-rg-MP0440-Ab-1/ GM-Tg-rg-MP0440-Ab-2Anti-Rat FCRL6 monoclonal antibodyRat
GM-Tg-mg-MP0440-Ab-1/ GM-Tg-mg-MP0440-Ab-2Anti-Mouse FCRL6 monoclonal antibodyMouse
GM-Tg-cynog-MP0440-Ab-1/ GM-Tg-cynog-MP0440-Ab-2Anti-Cynomolgus/ Rhesus macaque FCRL6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0440-Ab-1/ GM-Tg-felg-MP0440-Ab-2Anti-Feline FCRL6 monoclonal antibodyFeline
GM-Tg-cang-MP0440-Ab-1/ GM-Tg-cang-MP0440-Ab-2Anti-Canine FCRL6 monoclonal antibodyCanine
GM-Tg-bovg-MP0440-Ab-1/ GM-Tg-bovg-MP0440-Ab-2Anti-Bovine FCRL6 monoclonal antibodyBovine
GM-Tg-equg-MP0440-Ab-1/ GM-Tg-equg-MP0440-Ab-2Anti-Equine FCRL6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0440-Ab-1/ GM-Tg-hg-MP0440-Ab-2; GM-Tg-rg-MP0440-Ab-1/ GM-Tg-rg-MP0440-Ab-2;
GM-Tg-mg-MP0440-Ab-1/ GM-Tg-mg-MP0440-Ab-2; GM-Tg-cynog-MP0440-Ab-1/ GM-Tg-cynog-MP0440-Ab-2;
GM-Tg-felg-MP0440-Ab-1/ GM-Tg-felg-MP0440-Ab-2; GM-Tg-cang-MP0440-Ab-1/ GM-Tg-cang-MP0440-Ab-2;
GM-Tg-bovg-MP0440-Ab-1/ GM-Tg-bovg-MP0440-Ab-2; GM-Tg-equg-MP0440-Ab-1/ GM-Tg-equg-MP0440-Ab-2
Products NameAnti-FCRL6 monoclonal antibody
Formatmab
Target NameFCRL6
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FCRL6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species FCRL6/ FcRH6 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0440
    Target NameFCRL6
    Gene ID343413,677296,305103,719486,524565
    Gene Symbol and SynonymsFcRH6,FCRL6,Gp42,mIFGP6,moFcRH6
    Uniprot AccessionQ6DN72,P23505
    Uniprot Entry NameFCRL6_HUMAN,GP42_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000181036
    Target ClassificationN/A

    The target: FCRL6, gene name: FCRL6, also named as FcRH6. Enables MHC class II protein binding activity and protein phosphatase binding activity. Predicted to be involved in cell surface receptor signaling pathway. Located in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.