Anti-FLRT3/ HH21 monoclonal antibody

Anti-FLRT3/ HH21 antibody for FACS & in-vivo assay

Target products collectionGo to FLRT3/FLRT3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0445-Ab-1/ GM-Tg-hg-MP0445-Ab-2Anti-Human FLRT3 monoclonal antibodyHuman
GM-Tg-rg-MP0445-Ab-1/ GM-Tg-rg-MP0445-Ab-2Anti-Rat FLRT3 monoclonal antibodyRat
GM-Tg-mg-MP0445-Ab-1/ GM-Tg-mg-MP0445-Ab-2Anti-Mouse FLRT3 monoclonal antibodyMouse
GM-Tg-cynog-MP0445-Ab-1/ GM-Tg-cynog-MP0445-Ab-2Anti-Cynomolgus/ Rhesus macaque FLRT3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0445-Ab-1/ GM-Tg-felg-MP0445-Ab-2Anti-Feline FLRT3 monoclonal antibodyFeline
GM-Tg-cang-MP0445-Ab-1/ GM-Tg-cang-MP0445-Ab-2Anti-Canine FLRT3 monoclonal antibodyCanine
GM-Tg-bovg-MP0445-Ab-1/ GM-Tg-bovg-MP0445-Ab-2Anti-Bovine FLRT3 monoclonal antibodyBovine
GM-Tg-equg-MP0445-Ab-1/ GM-Tg-equg-MP0445-Ab-2Anti-Equine FLRT3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0445-Ab-1/ GM-Tg-hg-MP0445-Ab-2; GM-Tg-rg-MP0445-Ab-1/ GM-Tg-rg-MP0445-Ab-2;
GM-Tg-mg-MP0445-Ab-1/ GM-Tg-mg-MP0445-Ab-2; GM-Tg-cynog-MP0445-Ab-1/ GM-Tg-cynog-MP0445-Ab-2;
GM-Tg-felg-MP0445-Ab-1/ GM-Tg-felg-MP0445-Ab-2; GM-Tg-cang-MP0445-Ab-1/ GM-Tg-cang-MP0445-Ab-2;
GM-Tg-bovg-MP0445-Ab-1/ GM-Tg-bovg-MP0445-Ab-2; GM-Tg-equg-MP0445-Ab-1/ GM-Tg-equg-MP0445-Ab-2
Products NameAnti-FLRT3 monoclonal antibody
Formatmab
Target NameFLRT3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FLRT3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species FLRT3/ HH21 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP003825human FLRT3 Lentivirus plasmid
    ORF Viral VectorvGMLP003825human FLRT3 Lentivirus particle


    Target information

    Target IDGM-MP0445
    Target NameFLRT3
    Gene ID23767,71436,366205,694694,477149,101095003,529416,100051056
    Gene Symbol and Synonyms5530600M07Rik,C430047I10Rik,FLRT3,HH21,mKIAA1469,RGD1566005
    Uniprot AccessionQ9NZU0,B1H234
    Uniprot Entry NameFLRT3_HUMAN,FLRT3_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000125848
    Target ClassificationN/A

    The target: FLRT3, gene name: FLRT3, also named as HH21. This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.