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Anti-FXYD7 monoclonal antibody
Anti-FXYD7 antibody for FACS & in-vivo assay
Go to FXYD7/FXYD7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0459-Ab-1/ GM-Tg-hg-MP0459-Ab-2 | Anti-Human FXYD7 monoclonal antibody | Human |
| GM-Tg-rg-MP0459-Ab-1/ GM-Tg-rg-MP0459-Ab-2 | Anti-Rat FXYD7 monoclonal antibody | Rat |
| GM-Tg-mg-MP0459-Ab-1/ GM-Tg-mg-MP0459-Ab-2 | Anti-Mouse FXYD7 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0459-Ab-1/ GM-Tg-cynog-MP0459-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FXYD7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0459-Ab-1/ GM-Tg-felg-MP0459-Ab-2 | Anti-Feline FXYD7 monoclonal antibody | Feline |
| GM-Tg-cang-MP0459-Ab-1/ GM-Tg-cang-MP0459-Ab-2 | Anti-Canine FXYD7 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0459-Ab-1/ GM-Tg-bovg-MP0459-Ab-2 | Anti-Bovine FXYD7 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0459-Ab-1/ GM-Tg-equg-MP0459-Ab-2 | Anti-Equine FXYD7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0459-Ab-1/ GM-Tg-hg-MP0459-Ab-2; GM-Tg-rg-MP0459-Ab-1/ GM-Tg-rg-MP0459-Ab-2; GM-Tg-mg-MP0459-Ab-1/ GM-Tg-mg-MP0459-Ab-2; GM-Tg-cynog-MP0459-Ab-1/ GM-Tg-cynog-MP0459-Ab-2; GM-Tg-felg-MP0459-Ab-1/ GM-Tg-felg-MP0459-Ab-2; GM-Tg-cang-MP0459-Ab-1/ GM-Tg-cang-MP0459-Ab-2; GM-Tg-bovg-MP0459-Ab-1/ GM-Tg-bovg-MP0459-Ab-2; GM-Tg-equg-MP0459-Ab-1/ GM-Tg-equg-MP0459-Ab-2 |
| Products Name | Anti-FXYD7 monoclonal antibody |
| Format | mab |
| Target Name | FXYD7 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FXYD7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species FXYD7 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0459 |
| Target Name | FXYD7 |
| Gene ID | 53822,57780,63848,718457,106559193,101088634,616128,111775184 |
| Gene Symbol and Synonyms | 1110035I01Rik,FXYD7 |
| Uniprot Accession | P58549,P59649,Q3ZBJ3 |
| Uniprot Entry Name | FXYD7_HUMAN,FXYD7_RAT,FXYD7_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000221946 |
| Target Classification | N/A |
The target: FXYD7, gene name: FXYD7, also named as . This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, FXYD7, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., [email protected]., Dec 2000].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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