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Anti-FZD5/ C2orf31/ HFZ5 monoclonal antibody
Anti-FZD5/ C2orf31/ HFZ5 antibody for FACS & in-vivo assay
Go to FZD5/FZD5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0464-Ab-1/ GM-Tg-hg-MP0464-Ab-2 | Anti-Human FZD5 monoclonal antibody | Human |
| GM-Tg-rg-MP0464-Ab-1/ GM-Tg-rg-MP0464-Ab-2 | Anti-Rat FZD5 monoclonal antibody | Rat |
| GM-Tg-mg-MP0464-Ab-1/ GM-Tg-mg-MP0464-Ab-2 | Anti-Mouse FZD5 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0464-Ab-1/ GM-Tg-cynog-MP0464-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FZD5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0464-Ab-1/ GM-Tg-felg-MP0464-Ab-2 | Anti-Feline FZD5 monoclonal antibody | Feline |
| GM-Tg-cang-MP0464-Ab-1/ GM-Tg-cang-MP0464-Ab-2 | Anti-Canine FZD5 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0464-Ab-1/ GM-Tg-bovg-MP0464-Ab-2 | Anti-Bovine FZD5 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0464-Ab-1/ GM-Tg-equg-MP0464-Ab-2 | Anti-Equine FZD5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0464-Ab-1/ GM-Tg-hg-MP0464-Ab-2; GM-Tg-rg-MP0464-Ab-1/ GM-Tg-rg-MP0464-Ab-2; GM-Tg-mg-MP0464-Ab-1/ GM-Tg-mg-MP0464-Ab-2; GM-Tg-cynog-MP0464-Ab-1/ GM-Tg-cynog-MP0464-Ab-2; GM-Tg-felg-MP0464-Ab-1/ GM-Tg-felg-MP0464-Ab-2; GM-Tg-cang-MP0464-Ab-1/ GM-Tg-cang-MP0464-Ab-2; GM-Tg-bovg-MP0464-Ab-1/ GM-Tg-bovg-MP0464-Ab-2; GM-Tg-equg-MP0464-Ab-1/ GM-Tg-equg-MP0464-Ab-2 |
| Products Name | Anti-FZD5 monoclonal antibody |
| Format | mab |
| Target Name | FZD5 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FZD5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species FZD5/ C2orf31/ HFZ5 VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-MP0464-Ag-1 | frizzled class receptor 5 (FZD5) protein |
| ORF Viral Vector | pGMLPm004353 | mouse Fzd5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004353 | mouse Fzd5 Lentivirus particle |
Target information
| Target ID | GM-MP0464 |
| Target Name | FZD5 |
| Gene ID | 7855,14367,317674,710796,119863906,101097508,538536,100146215 |
| Gene Symbol and Synonyms | 5330434N09Rik,C2orf31,Fz-5,Fz5,FZD5,HFZ5,LOC119863906,mFz5 |
| Uniprot Accession | Q13467,Q8CHL0 |
| Uniprot Entry Name | FZD5_HUMAN,FZD5_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000163251 |
| Target Classification | N/A |
The target: FZD5, gene name: FZD5, also named as C2orf31, HFZ5. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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