Anti-GAPT/ C5orf29 monoclonal antibody

Anti-GAPT/ C5orf29 antibody for FACS & in-vivo assay

Target products collectionGo to GAPT/GAPT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0473-Ab-1/ GM-Tg-hg-MP0473-Ab-2Anti-Human GAPT monoclonal antibodyHuman
GM-Tg-rg-MP0473-Ab-1/ GM-Tg-rg-MP0473-Ab-2Anti-Rat GAPT monoclonal antibodyRat
GM-Tg-mg-MP0473-Ab-1/ GM-Tg-mg-MP0473-Ab-2Anti-Mouse GAPT monoclonal antibodyMouse
GM-Tg-cynog-MP0473-Ab-1/ GM-Tg-cynog-MP0473-Ab-2Anti-Cynomolgus/ Rhesus macaque GAPT monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0473-Ab-1/ GM-Tg-felg-MP0473-Ab-2Anti-Feline GAPT monoclonal antibodyFeline
GM-Tg-cang-MP0473-Ab-1/ GM-Tg-cang-MP0473-Ab-2Anti-Canine GAPT monoclonal antibodyCanine
GM-Tg-bovg-MP0473-Ab-1/ GM-Tg-bovg-MP0473-Ab-2Anti-Bovine GAPT monoclonal antibodyBovine
GM-Tg-equg-MP0473-Ab-1/ GM-Tg-equg-MP0473-Ab-2Anti-Equine GAPT monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0473-Ab-1/ GM-Tg-hg-MP0473-Ab-2; GM-Tg-rg-MP0473-Ab-1/ GM-Tg-rg-MP0473-Ab-2;
GM-Tg-mg-MP0473-Ab-1/ GM-Tg-mg-MP0473-Ab-2; GM-Tg-cynog-MP0473-Ab-1/ GM-Tg-cynog-MP0473-Ab-2;
GM-Tg-felg-MP0473-Ab-1/ GM-Tg-felg-MP0473-Ab-2; GM-Tg-cang-MP0473-Ab-1/ GM-Tg-cang-MP0473-Ab-2;
GM-Tg-bovg-MP0473-Ab-1/ GM-Tg-bovg-MP0473-Ab-2; GM-Tg-equg-MP0473-Ab-1/ GM-Tg-equg-MP0473-Ab-2
Products NameAnti-GAPT monoclonal antibody
Formatmab
Target NameGAPT
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GAPT benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GAPT/ C5orf29 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0473
    Target NameGAPT
    Gene ID202309,238875,686075,708948,100683936,101092333,784765,100060771
    Gene Symbol and Synonyms9830130M13Rik,C5orf29,GAPT
    Uniprot AccessionQ8N292
    Uniprot Entry NameGAPT_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000175857
    Target ClassificationN/A

    The target: GAPT, gene name: GAPT, also named as C5orf29. Predicted to be involved in B cell homeostasis and B cell proliferation involved in immune response. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.