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Anti-GGT5/ GGL/ GGT 5 monoclonal antibody
Anti-GGT5/ GGL/ GGT 5 antibody for FACS & in-vivo assay
Go to GGT5/GGT5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0481-Ab-1/ GM-Tg-hg-MP0481-Ab-2 | Anti-Human GGT5 monoclonal antibody | Human |
| GM-Tg-rg-MP0481-Ab-1/ GM-Tg-rg-MP0481-Ab-2 | Anti-Rat GGT5 monoclonal antibody | Rat |
| GM-Tg-mg-MP0481-Ab-1/ GM-Tg-mg-MP0481-Ab-2 | Anti-Mouse GGT5 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0481-Ab-1/ GM-Tg-cynog-MP0481-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GGT5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0481-Ab-1/ GM-Tg-felg-MP0481-Ab-2 | Anti-Feline GGT5 monoclonal antibody | Feline |
| GM-Tg-cang-MP0481-Ab-1/ GM-Tg-cang-MP0481-Ab-2 | Anti-Canine GGT5 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0481-Ab-1/ GM-Tg-bovg-MP0481-Ab-2 | Anti-Bovine GGT5 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0481-Ab-1/ GM-Tg-equg-MP0481-Ab-2 | Anti-Equine GGT5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0481-Ab-1/ GM-Tg-hg-MP0481-Ab-2; GM-Tg-rg-MP0481-Ab-1/ GM-Tg-rg-MP0481-Ab-2; GM-Tg-mg-MP0481-Ab-1/ GM-Tg-mg-MP0481-Ab-2; GM-Tg-cynog-MP0481-Ab-1/ GM-Tg-cynog-MP0481-Ab-2; GM-Tg-felg-MP0481-Ab-1/ GM-Tg-felg-MP0481-Ab-2; GM-Tg-cang-MP0481-Ab-1/ GM-Tg-cang-MP0481-Ab-2; GM-Tg-bovg-MP0481-Ab-1/ GM-Tg-bovg-MP0481-Ab-2; GM-Tg-equg-MP0481-Ab-1/ GM-Tg-equg-MP0481-Ab-2 |
| Products Name | Anti-GGT5 monoclonal antibody |
| Format | mab |
| Target Name | GGT5 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GGT5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species GGT5/ GGL/ GGT 5 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP0481 |
| Target Name | GGT5 |
| Gene ID | 2687,23887,29566,486401,101082015,787326,100050259 |
| Gene Symbol and Synonyms | GGL,GGT 5,GGT-REL,GGT5,Ggta1,GGTLA1 |
| Uniprot Accession | P36269,Q9QWE9 |
| Uniprot Entry Name | GGT5_HUMAN,GGT5_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000099998 |
| Target Classification | N/A |
The target: GGT5, gene name: GGT5, also named as GGL, GGT 5, GGT-REL, GGTLA1. This gene is a member of the gamma-glutamyl transpeptidase gene family, and some reports indicate that it is capable of cleaving the gamma-glutamyl moiety of glutathione. The protein encoded by this gene is synthesized as a single, catalytically-inactive polypeptide, that is processed post-transcriptionally to form a heavy and light subunit, with the catalytic activity contained within the small subunit. The encoded enzyme is able to convert leukotriene C4 to leukotriene D4, but appears to have distinct substrate specificity compared to gamma-glutamyl transpeptidase. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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