Anti-GPM6A/ GPM6/ M6A monoclonal antibody

Anti-GPM6A/ GPM6/ M6A antibody for FACS & in-vivo assay

Target products collectionGo to GPM6A/GPM6A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0496-Ab-1/ GM-Tg-hg-MP0496-Ab-2Anti-Human GPM6A monoclonal antibodyHuman
GM-Tg-rg-MP0496-Ab-1/ GM-Tg-rg-MP0496-Ab-2Anti-Rat GPM6A monoclonal antibodyRat
GM-Tg-mg-MP0496-Ab-1/ GM-Tg-mg-MP0496-Ab-2Anti-Mouse GPM6A monoclonal antibodyMouse
GM-Tg-cynog-MP0496-Ab-1/ GM-Tg-cynog-MP0496-Ab-2Anti-Cynomolgus/ Rhesus macaque GPM6A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0496-Ab-1/ GM-Tg-felg-MP0496-Ab-2Anti-Feline GPM6A monoclonal antibodyFeline
GM-Tg-cang-MP0496-Ab-1/ GM-Tg-cang-MP0496-Ab-2Anti-Canine GPM6A monoclonal antibodyCanine
GM-Tg-bovg-MP0496-Ab-1/ GM-Tg-bovg-MP0496-Ab-2Anti-Bovine GPM6A monoclonal antibodyBovine
GM-Tg-equg-MP0496-Ab-1/ GM-Tg-equg-MP0496-Ab-2Anti-Equine GPM6A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0496-Ab-1/ GM-Tg-hg-MP0496-Ab-2; GM-Tg-rg-MP0496-Ab-1/ GM-Tg-rg-MP0496-Ab-2;
GM-Tg-mg-MP0496-Ab-1/ GM-Tg-mg-MP0496-Ab-2; GM-Tg-cynog-MP0496-Ab-1/ GM-Tg-cynog-MP0496-Ab-2;
GM-Tg-felg-MP0496-Ab-1/ GM-Tg-felg-MP0496-Ab-2; GM-Tg-cang-MP0496-Ab-1/ GM-Tg-cang-MP0496-Ab-2;
GM-Tg-bovg-MP0496-Ab-1/ GM-Tg-bovg-MP0496-Ab-2; GM-Tg-equg-MP0496-Ab-1/ GM-Tg-equg-MP0496-Ab-2
Products NameAnti-GPM6A monoclonal antibody
Formatmab
Target NameGPM6A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPM6A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GPM6A/ GPM6/ M6A VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP000127human GPM6A Lentivirus plasmid
    ORF Viral VectorvGMLP000127human GPM6A Lentivirus particle
    ORF Viral VectorpGMLPm002461mouse Gpm6a Lentivirus plasmid
    ORF Viral VectorvGMLPm002461mouse Gpm6a Lentivirus particle


    Target information

    Target IDGM-MP0496
    Target NameGPM6A
    Gene ID2823,234267,306439,698488,475641,101080277,507389,100051492
    Gene Symbol and SynonymsGPM6,GPM6A,M6A
    Uniprot AccessionP51674,Q812E9,Q0VD07
    Uniprot Entry NameGPM6A_HUMAN,GPM6A_RAT,GPM6A_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000150625
    Target ClassificationN/A

    The target: GPM6A, gene name: GPM6A, also named as GPM6, M6A. Predicted to enable calcium channel activity. Involved in neuron migration and stem cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.