Anti-AGRF5/ ADGRF5/ GPR116 monoclonal antibody

Anti-AGRF5/ ADGRF5/ GPR116 antibody for FACS & in-vivo assay

Target products collectionGo to ADGRF5/ADGRF5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0502-Ab-1/ GM-Tg-hg-MP0502-Ab-2Anti-Human ADGRF5 monoclonal antibodyHuman
GM-Tg-rg-MP0502-Ab-1/ GM-Tg-rg-MP0502-Ab-2Anti-Rat ADGRF5 monoclonal antibodyRat
GM-Tg-mg-MP0502-Ab-1/ GM-Tg-mg-MP0502-Ab-2Anti-Mouse ADGRF5 monoclonal antibodyMouse
GM-Tg-cynog-MP0502-Ab-1/ GM-Tg-cynog-MP0502-Ab-2Anti-Cynomolgus/ Rhesus macaque ADGRF5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0502-Ab-1/ GM-Tg-felg-MP0502-Ab-2Anti-Feline ADGRF5 monoclonal antibodyFeline
GM-Tg-cang-MP0502-Ab-1/ GM-Tg-cang-MP0502-Ab-2Anti-Canine ADGRF5 monoclonal antibodyCanine
GM-Tg-bovg-MP0502-Ab-1/ GM-Tg-bovg-MP0502-Ab-2Anti-Bovine ADGRF5 monoclonal antibodyBovine
GM-Tg-equg-MP0502-Ab-1/ GM-Tg-equg-MP0502-Ab-2Anti-Equine ADGRF5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0502-Ab-1/ GM-Tg-hg-MP0502-Ab-2; GM-Tg-rg-MP0502-Ab-1/ GM-Tg-rg-MP0502-Ab-2;
GM-Tg-mg-MP0502-Ab-1/ GM-Tg-mg-MP0502-Ab-2; GM-Tg-cynog-MP0502-Ab-1/ GM-Tg-cynog-MP0502-Ab-2;
GM-Tg-felg-MP0502-Ab-1/ GM-Tg-felg-MP0502-Ab-2; GM-Tg-cang-MP0502-Ab-1/ GM-Tg-cang-MP0502-Ab-2;
GM-Tg-bovg-MP0502-Ab-1/ GM-Tg-bovg-MP0502-Ab-2; GM-Tg-equg-MP0502-Ab-1/ GM-Tg-equg-MP0502-Ab-2
Products NameAnti-ADGRF5 monoclonal antibody
Formatmab
Target NameADGRF5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ADGRF5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species AGRF5/ ADGRF5/ GPR116 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0502
    Target NameADGRF5
    Gene ID221395,224792,245977,704887,474926,101101312,532674,100068417
    Gene Symbol and Synonyms8430401C09Rik,9330185D23,ADGRF5,GPR116,Gprhep,Ig-Hepta,KPG_001,mKIAA0758
    Uniprot AccessionQ8IZF2,Q9WVT0
    Uniprot Entry NameAGRF5_HUMAN,AGRF5_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000069122
    Target ClassificationGPCR

    The target: ADGRF5, gene name: ADGRF5, also named as GPR116, KPG_001. Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cell surface receptor signaling pathway. Predicted to act upstream of or within several processes, including glomerular filtration; pharyngeal arch artery morphogenesis; and surfactant homeostasis. Located in cell surface and cytoplasmic vesicle. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.