Anti-AGRD1/ ADGRD1/ GPR133 monoclonal antibody

Anti-AGRD1/ ADGRD1/ GPR133 antibody for FACS & in-vivo assay

Target products collectionGo to ADGRD1/ADGRD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0506-Ab-1/ GM-Tg-hg-MP0506-Ab-2Anti-Human ADGRD1 monoclonal antibodyHuman
GM-Tg-rg-MP0506-Ab-1/ GM-Tg-rg-MP0506-Ab-2Anti-Rat ADGRD1 monoclonal antibodyRat
GM-Tg-mg-MP0506-Ab-1/ GM-Tg-mg-MP0506-Ab-2Anti-Mouse ADGRD1 monoclonal antibodyMouse
GM-Tg-cynog-MP0506-Ab-1/ GM-Tg-cynog-MP0506-Ab-2Anti-Cynomolgus/ Rhesus macaque ADGRD1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0506-Ab-1/ GM-Tg-felg-MP0506-Ab-2Anti-Feline ADGRD1 monoclonal antibodyFeline
GM-Tg-cang-MP0506-Ab-1/ GM-Tg-cang-MP0506-Ab-2Anti-Canine ADGRD1 monoclonal antibodyCanine
GM-Tg-bovg-MP0506-Ab-1/ GM-Tg-bovg-MP0506-Ab-2Anti-Bovine ADGRD1 monoclonal antibodyBovine
GM-Tg-equg-MP0506-Ab-1/ GM-Tg-equg-MP0506-Ab-2Anti-Equine ADGRD1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0506-Ab-1/ GM-Tg-hg-MP0506-Ab-2; GM-Tg-rg-MP0506-Ab-1/ GM-Tg-rg-MP0506-Ab-2;
GM-Tg-mg-MP0506-Ab-1/ GM-Tg-mg-MP0506-Ab-2; GM-Tg-cynog-MP0506-Ab-1/ GM-Tg-cynog-MP0506-Ab-2;
GM-Tg-felg-MP0506-Ab-1/ GM-Tg-felg-MP0506-Ab-2; GM-Tg-cang-MP0506-Ab-1/ GM-Tg-cang-MP0506-Ab-2;
GM-Tg-bovg-MP0506-Ab-1/ GM-Tg-bovg-MP0506-Ab-2; GM-Tg-equg-MP0506-Ab-1/ GM-Tg-equg-MP0506-Ab-2
Products NameAnti-ADGRD1 monoclonal antibody
Formatmab
Target NameADGRD1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ADGRD1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species AGRD1/ ADGRD1/ GPR133 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMAD000540human ADGRD1 Adenovirus plasmid
    ORF Viral VectorvGMAD000540human ADGRD1 Adenovirus particle


    Target information

    Target IDGM-MP0506
    Target NameADGRD1
    Gene ID283383,243277,689257,709387,486229,101080410,528174,100062695
    Gene Symbol and SynonymsADGRD1,E230012M21Rik,GPR133,PGR25
    Uniprot AccessionQ6QNK2,A6QLU6
    Uniprot Entry NameAGRD1_HUMAN,AGRD1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000111452
    Target ClassificationGPCR

    The target: ADGRD1, gene name: ADGRD1, also named as GPR133, PGR25. 0.



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.