Anti-GPR15/ BOB monoclonal antibody

Anti-GPR15/ BOB antibody for FACS & in-vivo assay

Target products collectionGo to GPR15/GPR15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0514-Ab-1/ GM-Tg-hg-MP0514-Ab-2Anti-Human GPR15 monoclonal antibodyHuman
GM-Tg-rg-MP0514-Ab-1/ GM-Tg-rg-MP0514-Ab-2Anti-Rat GPR15 monoclonal antibodyRat
GM-Tg-mg-MP0514-Ab-1/ GM-Tg-mg-MP0514-Ab-2Anti-Mouse GPR15 monoclonal antibodyMouse
GM-Tg-cynog-MP0514-Ab-1/ GM-Tg-cynog-MP0514-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR15 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0514-Ab-1/ GM-Tg-felg-MP0514-Ab-2Anti-Feline GPR15 monoclonal antibodyFeline
GM-Tg-cang-MP0514-Ab-1/ GM-Tg-cang-MP0514-Ab-2Anti-Canine GPR15 monoclonal antibodyCanine
GM-Tg-bovg-MP0514-Ab-1/ GM-Tg-bovg-MP0514-Ab-2Anti-Bovine GPR15 monoclonal antibodyBovine
GM-Tg-equg-MP0514-Ab-1/ GM-Tg-equg-MP0514-Ab-2Anti-Equine GPR15 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0514-Ab-1/ GM-Tg-hg-MP0514-Ab-2; GM-Tg-rg-MP0514-Ab-1/ GM-Tg-rg-MP0514-Ab-2;
GM-Tg-mg-MP0514-Ab-1/ GM-Tg-mg-MP0514-Ab-2; GM-Tg-cynog-MP0514-Ab-1/ GM-Tg-cynog-MP0514-Ab-2;
GM-Tg-felg-MP0514-Ab-1/ GM-Tg-felg-MP0514-Ab-2; GM-Tg-cang-MP0514-Ab-1/ GM-Tg-cang-MP0514-Ab-2;
GM-Tg-bovg-MP0514-Ab-1/ GM-Tg-bovg-MP0514-Ab-2; GM-Tg-equg-MP0514-Ab-1/ GM-Tg-equg-MP0514-Ab-2
Products NameAnti-GPR15 monoclonal antibody
Formatmab
Target NameGPR15
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR15 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GPR15/ BOB VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0514
    Target NameGPR15
    Gene ID2838,71223,288181,698718,111093726,111556184,538740,100072420
    Gene Symbol and Synonyms4933439K08Rik,BOB,GPR15
    Uniprot AccessionP49685,O97663
    Uniprot Entry NameGPR15_HUMAN,GPR15_MACMU
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000154165
    Target ClassificationN/A

    The target: GPR15, gene name: GPR15, also named as BOB. This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.