Anti-GP157/ GPR157 monoclonal antibody

Anti-GP157/ GPR157 antibody for FACS & in-vivo assay

Target products collectionGo to GPR157/GPR157 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0518-Ab-1/ GM-Tg-hg-MP0518-Ab-2Anti-Human GPR157 monoclonal antibodyHuman
GM-Tg-rg-MP0518-Ab-1/ GM-Tg-rg-MP0518-Ab-2Anti-Rat GPR157 monoclonal antibodyRat
GM-Tg-mg-MP0518-Ab-1/ GM-Tg-mg-MP0518-Ab-2Anti-Mouse GPR157 monoclonal antibodyMouse
GM-Tg-cynog-MP0518-Ab-1/ GM-Tg-cynog-MP0518-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR157 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0518-Ab-1/ GM-Tg-felg-MP0518-Ab-2Anti-Feline GPR157 monoclonal antibodyFeline
GM-Tg-cang-MP0518-Ab-1/ GM-Tg-cang-MP0518-Ab-2Anti-Canine GPR157 monoclonal antibodyCanine
GM-Tg-bovg-MP0518-Ab-1/ GM-Tg-bovg-MP0518-Ab-2Anti-Bovine GPR157 monoclonal antibodyBovine
GM-Tg-equg-MP0518-Ab-1/ GM-Tg-equg-MP0518-Ab-2Anti-Equine GPR157 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0518-Ab-1/ GM-Tg-hg-MP0518-Ab-2; GM-Tg-rg-MP0518-Ab-1/ GM-Tg-rg-MP0518-Ab-2;
GM-Tg-mg-MP0518-Ab-1/ GM-Tg-mg-MP0518-Ab-2; GM-Tg-cynog-MP0518-Ab-1/ GM-Tg-cynog-MP0518-Ab-2;
GM-Tg-felg-MP0518-Ab-1/ GM-Tg-felg-MP0518-Ab-2; GM-Tg-cang-MP0518-Ab-1/ GM-Tg-cang-MP0518-Ab-2;
GM-Tg-bovg-MP0518-Ab-1/ GM-Tg-bovg-MP0518-Ab-2; GM-Tg-equg-MP0518-Ab-1/ GM-Tg-equg-MP0518-Ab-2
Products NameAnti-GPR157 monoclonal antibody
Formatmab
Target NameGPR157
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR157 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GP157/ GPR157 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0518
    Target NameGPR157
    Gene ID80045,269604,313725,722176,608460,101097821,538468,100057687
    Gene Symbol and SynonymsF730108M23Rik,GPR157
    Uniprot AccessionQ5UAW9,Q5FVG1
    Uniprot Entry NameGP157_HUMAN,GP157_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseBreast Cancer
    Gene EnsemblENSG00000180758
    Target ClassificationGPCR

    The target: GPR157, gene name: GPR157, also named as . Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway and radial glial cell differentiation. Predicted to be located in ciliary membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.