Anti-GP173/ GPR173/ SREB3 monoclonal antibody

Anti-GP173/ GPR173/ SREB3 antibody for FACS & in-vivo assay

Target products collectionGo to GPR173/GPR173 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0523-Ab-1/ GM-Tg-hg-MP0523-Ab-2Anti-Human GPR173 monoclonal antibodyHuman
GM-Tg-rg-MP0523-Ab-1/ GM-Tg-rg-MP0523-Ab-2Anti-Rat GPR173 monoclonal antibodyRat
GM-Tg-mg-MP0523-Ab-1/ GM-Tg-mg-MP0523-Ab-2Anti-Mouse GPR173 monoclonal antibodyMouse
GM-Tg-cynog-MP0523-Ab-1/ GM-Tg-cynog-MP0523-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR173 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0523-Ab-1/ GM-Tg-felg-MP0523-Ab-2Anti-Feline GPR173 monoclonal antibodyFeline
GM-Tg-cang-MP0523-Ab-1/ GM-Tg-cang-MP0523-Ab-2Anti-Canine GPR173 monoclonal antibodyCanine
GM-Tg-bovg-MP0523-Ab-1/ GM-Tg-bovg-MP0523-Ab-2Anti-Bovine GPR173 monoclonal antibodyBovine
GM-Tg-equg-MP0523-Ab-1/ GM-Tg-equg-MP0523-Ab-2Anti-Equine GPR173 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0523-Ab-1/ GM-Tg-hg-MP0523-Ab-2; GM-Tg-rg-MP0523-Ab-1/ GM-Tg-rg-MP0523-Ab-2;
GM-Tg-mg-MP0523-Ab-1/ GM-Tg-mg-MP0523-Ab-2; GM-Tg-cynog-MP0523-Ab-1/ GM-Tg-cynog-MP0523-Ab-2;
GM-Tg-felg-MP0523-Ab-1/ GM-Tg-felg-MP0523-Ab-2; GM-Tg-cang-MP0523-Ab-1/ GM-Tg-cang-MP0523-Ab-2;
GM-Tg-bovg-MP0523-Ab-1/ GM-Tg-bovg-MP0523-Ab-2; GM-Tg-equg-MP0523-Ab-1/ GM-Tg-equg-MP0523-Ab-2
Products NameAnti-GPR173 monoclonal antibody
Formatmab
Target NameGPR173
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR173 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GP173/ GPR173/ SREB3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0523
    Target NameGPR173
    Gene ID54328,70771,64021,698645,491892,101089675,515148,102147853
    Gene Symbol and Synonyms3230401K02Rik,GPR173,SREB3
    Uniprot AccessionQ9NS66,Q9JJH2,Q5E9H8
    Uniprot Entry NameGP173_HUMAN,GP173_RAT,GP173_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000184194
    Target ClassificationGPCR

    The target: GPR173, gene name: GPR173, also named as SREB3. This gene encodes a member of the G-protein coupled receptor 1 family. This protein contains 7 transmembrane domains and conserved cysteine residues. [provided by RefSeq, Nov 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.