Anti-GPR22 monoclonal antibody

Anti-GPR22 antibody for FACS & in-vivo assay

Target products collectionGo to GPR22/GPR22 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0528-Ab-1/ GM-Tg-hg-MP0528-Ab-2Anti-Human GPR22 monoclonal antibodyHuman
GM-Tg-rg-MP0528-Ab-1/ GM-Tg-rg-MP0528-Ab-2Anti-Rat GPR22 monoclonal antibodyRat
GM-Tg-mg-MP0528-Ab-1/ GM-Tg-mg-MP0528-Ab-2Anti-Mouse GPR22 monoclonal antibodyMouse
GM-Tg-cynog-MP0528-Ab-1/ GM-Tg-cynog-MP0528-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR22 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0528-Ab-1/ GM-Tg-felg-MP0528-Ab-2Anti-Feline GPR22 monoclonal antibodyFeline
GM-Tg-cang-MP0528-Ab-1/ GM-Tg-cang-MP0528-Ab-2Anti-Canine GPR22 monoclonal antibodyCanine
GM-Tg-bovg-MP0528-Ab-1/ GM-Tg-bovg-MP0528-Ab-2Anti-Bovine GPR22 monoclonal antibodyBovine
GM-Tg-equg-MP0528-Ab-1/ GM-Tg-equg-MP0528-Ab-2Anti-Equine GPR22 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0528-Ab-1/ GM-Tg-hg-MP0528-Ab-2; GM-Tg-rg-MP0528-Ab-1/ GM-Tg-rg-MP0528-Ab-2;
GM-Tg-mg-MP0528-Ab-1/ GM-Tg-mg-MP0528-Ab-2; GM-Tg-cynog-MP0528-Ab-1/ GM-Tg-cynog-MP0528-Ab-2;
GM-Tg-felg-MP0528-Ab-1/ GM-Tg-felg-MP0528-Ab-2; GM-Tg-cang-MP0528-Ab-1/ GM-Tg-cang-MP0528-Ab-2;
GM-Tg-bovg-MP0528-Ab-1/ GM-Tg-bovg-MP0528-Ab-2; GM-Tg-equg-MP0528-Ab-1/ GM-Tg-equg-MP0528-Ab-2
Products NameAnti-GPR22 monoclonal antibody
Formatmab
Target NameGPR22
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR22 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GPR22 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0528
    Target NameGPR22
    Gene ID2845,73010,298944,699492,607459,101095564,783685,100146673
    Gene Symbol and Synonyms2900068K05Rik,GPR22
    Uniprot AccessionQ99680,D4A3U0
    Uniprot Entry NameGPR22_HUMAN,GPR22_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000172209
    Target ClassificationGPCR

    The target: GPR22, gene name: GPR22, also named as . This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.