Anti-GPR25 monoclonal antibody

Anti-GPR25 antibody for FACS & in-vivo assay

Target products collectionGo to GPR25/GPR25 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0529-Ab-1/ GM-Tg-hg-MP0529-Ab-2Anti-Human GPR25 monoclonal antibodyHuman
GM-Tg-rg-MP0529-Ab-1/ GM-Tg-rg-MP0529-Ab-2Anti-Rat GPR25 monoclonal antibodyRat
GM-Tg-mg-MP0529-Ab-1/ GM-Tg-mg-MP0529-Ab-2Anti-Mouse GPR25 monoclonal antibodyMouse
GM-Tg-cynog-MP0529-Ab-1/ GM-Tg-cynog-MP0529-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR25 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0529-Ab-1/ GM-Tg-felg-MP0529-Ab-2Anti-Feline GPR25 monoclonal antibodyFeline
GM-Tg-cang-MP0529-Ab-1/ GM-Tg-cang-MP0529-Ab-2Anti-Canine GPR25 monoclonal antibodyCanine
GM-Tg-bovg-MP0529-Ab-1/ GM-Tg-bovg-MP0529-Ab-2Anti-Bovine GPR25 monoclonal antibodyBovine
GM-Tg-equg-MP0529-Ab-1/ GM-Tg-equg-MP0529-Ab-2Anti-Equine GPR25 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0529-Ab-1/ GM-Tg-hg-MP0529-Ab-2; GM-Tg-rg-MP0529-Ab-1/ GM-Tg-rg-MP0529-Ab-2;
GM-Tg-mg-MP0529-Ab-1/ GM-Tg-mg-MP0529-Ab-2; GM-Tg-cynog-MP0529-Ab-1/ GM-Tg-cynog-MP0529-Ab-2;
GM-Tg-felg-MP0529-Ab-1/ GM-Tg-felg-MP0529-Ab-2; GM-Tg-cang-MP0529-Ab-1/ GM-Tg-cang-MP0529-Ab-2;
GM-Tg-bovg-MP0529-Ab-1/ GM-Tg-bovg-MP0529-Ab-2; GM-Tg-equg-MP0529-Ab-1/ GM-Tg-equg-MP0529-Ab-2
Products NameAnti-GPR25 monoclonal antibody
Formatmab
Target NameGPR25
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR25 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GPR25 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0529
    Target NameGPR25
    Gene ID2848,383563,363993,709001,101098111,107133259,111771301
    Gene Symbol and SynonymsGm1300,GPR25
    Uniprot AccessionO00155
    Uniprot Entry NameGPR25_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000170128
    Target ClassificationGPCR

    The target: GPR25, gene name: GPR25, also named as . This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. This gene has been linked to arterial stiffness. [provided by RefSeq, Nov 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.