Anti-AGRV1/ ADGRV1/FEB4 monoclonal antibody

Anti-AGRV1/ ADGRV1/FEB4 antibody for FACS & in-vivo assay

Target products collectionGo to ADGRV1/ADGRV1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0550-Ab-1/ GM-Tg-hg-MP0550-Ab-2Anti-Human ADGRV1 monoclonal antibodyHuman
GM-Tg-rg-MP0550-Ab-1/ GM-Tg-rg-MP0550-Ab-2Anti-Rat ADGRV1 monoclonal antibodyRat
GM-Tg-mg-MP0550-Ab-1/ GM-Tg-mg-MP0550-Ab-2Anti-Mouse ADGRV1 monoclonal antibodyMouse
GM-Tg-cynog-MP0550-Ab-1/ GM-Tg-cynog-MP0550-Ab-2Anti-Cynomolgus/ Rhesus macaque ADGRV1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0550-Ab-1/ GM-Tg-felg-MP0550-Ab-2Anti-Feline ADGRV1 monoclonal antibodyFeline
GM-Tg-cang-MP0550-Ab-1/ GM-Tg-cang-MP0550-Ab-2Anti-Canine ADGRV1 monoclonal antibodyCanine
GM-Tg-bovg-MP0550-Ab-1/ GM-Tg-bovg-MP0550-Ab-2Anti-Bovine ADGRV1 monoclonal antibodyBovine
GM-Tg-equg-MP0550-Ab-1/ GM-Tg-equg-MP0550-Ab-2Anti-Equine ADGRV1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0550-Ab-1/ GM-Tg-hg-MP0550-Ab-2; GM-Tg-rg-MP0550-Ab-1/ GM-Tg-rg-MP0550-Ab-2;
GM-Tg-mg-MP0550-Ab-1/ GM-Tg-mg-MP0550-Ab-2; GM-Tg-cynog-MP0550-Ab-1/ GM-Tg-cynog-MP0550-Ab-2;
GM-Tg-felg-MP0550-Ab-1/ GM-Tg-felg-MP0550-Ab-2; GM-Tg-cang-MP0550-Ab-1/ GM-Tg-cang-MP0550-Ab-2;
GM-Tg-bovg-MP0550-Ab-1/ GM-Tg-bovg-MP0550-Ab-2; GM-Tg-equg-MP0550-Ab-1/ GM-Tg-equg-MP0550-Ab-2
Products NameAnti-ADGRV1 monoclonal antibody
Formatmab
Target NameADGRV1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ADGRV1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species AGRV1/ ADGRV1/FEB4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0550
    Target NameADGRV1
    Gene ID84059,110789,100362255,697794,479153,101100444,537034,100073239
    Gene Symbol and SynonymsADGRV1,FEB4,Frings,GPR98,MASS1,Mgr1,RGD1562101,USH2B,USH2C,VLGR1,VLGR1b
    Uniprot AccessionQ8WXG9
    Uniprot Entry NameAGRV1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164199
    Target ClassificationN/A

    The target: ADGRV1, gene name: ADGRV1, also named as FEB4, GPR98, MASS1, USH2B, USH2C, VLGR1, VLGR1b. This gene encodes a member of the G-protein coupled receptor superfamily. The encoded protein contains a 7-transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in this gene are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.