Anti-ASTRB/ GRAMD1B/ LINC01059 monoclonal antibody

Anti-ASTRB/ GRAMD1B/ LINC01059 antibody for FACS & in-vivo assay

Target products collectionGo to GRAMD1B/GRAMD1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0556-Ab-1/ GM-Tg-hg-MP0556-Ab-2Anti-Human GRAMD1B monoclonal antibodyHuman
GM-Tg-rg-MP0556-Ab-1/ GM-Tg-rg-MP0556-Ab-2Anti-Rat GRAMD1B monoclonal antibodyRat
GM-Tg-mg-MP0556-Ab-1/ GM-Tg-mg-MP0556-Ab-2Anti-Mouse GRAMD1B monoclonal antibodyMouse
GM-Tg-cynog-MP0556-Ab-1/ GM-Tg-cynog-MP0556-Ab-2Anti-Cynomolgus/ Rhesus macaque GRAMD1B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0556-Ab-1/ GM-Tg-felg-MP0556-Ab-2Anti-Feline GRAMD1B monoclonal antibodyFeline
GM-Tg-cang-MP0556-Ab-1/ GM-Tg-cang-MP0556-Ab-2Anti-Canine GRAMD1B monoclonal antibodyCanine
GM-Tg-bovg-MP0556-Ab-1/ GM-Tg-bovg-MP0556-Ab-2Anti-Bovine GRAMD1B monoclonal antibodyBovine
GM-Tg-equg-MP0556-Ab-1/ GM-Tg-equg-MP0556-Ab-2Anti-Equine GRAMD1B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0556-Ab-1/ GM-Tg-hg-MP0556-Ab-2; GM-Tg-rg-MP0556-Ab-1/ GM-Tg-rg-MP0556-Ab-2;
GM-Tg-mg-MP0556-Ab-1/ GM-Tg-mg-MP0556-Ab-2; GM-Tg-cynog-MP0556-Ab-1/ GM-Tg-cynog-MP0556-Ab-2;
GM-Tg-felg-MP0556-Ab-1/ GM-Tg-felg-MP0556-Ab-2; GM-Tg-cang-MP0556-Ab-1/ GM-Tg-cang-MP0556-Ab-2;
GM-Tg-bovg-MP0556-Ab-1/ GM-Tg-bovg-MP0556-Ab-2; GM-Tg-equg-MP0556-Ab-1/ GM-Tg-equg-MP0556-Ab-2
Products NameAnti-GRAMD1B monoclonal antibody
Formatmab
Target NameGRAMD1B
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GRAMD1B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ASTRB/ GRAMD1B/ LINC01059 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0556
    Target NameGRAMD1B
    Gene ID57476,235283,300644,708497,489352,101092289,517332,100063638
    Gene Symbol and Synonyms3222402H23,A930008A22Rik,GRAMD1B,LINC01059,mKIAA1201,RGD1305443
    Uniprot AccessionQ3KR37
    Uniprot Entry NameASTRB_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000023171
    Target ClassificationN/A

    The target: GRAMD1B, gene name: GRAMD1B, also named as LINC01059. Predicted to enable cholesterol binding activity; cholesterol transfer activity; and phospholipid binding activity. Predicted to be involved in cellular response to cholesterol and cholesterol homeostasis. Located in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.