Anti-GRID1/ GluD1 monoclonal antibody

Anti-GRID1/ GluD1 antibody for FACS & in-vivo assay

Target products collectionGo to GRID1/GRID1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0558-Ab-1/ GM-Tg-hg-MP0558-Ab-2Anti-Human GRID1 monoclonal antibodyHuman
GM-Tg-rg-MP0558-Ab-1/ GM-Tg-rg-MP0558-Ab-2Anti-Rat GRID1 monoclonal antibodyRat
GM-Tg-mg-MP0558-Ab-1/ GM-Tg-mg-MP0558-Ab-2Anti-Mouse GRID1 monoclonal antibodyMouse
GM-Tg-cynog-MP0558-Ab-1/ GM-Tg-cynog-MP0558-Ab-2Anti-Cynomolgus/ Rhesus macaque GRID1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0558-Ab-1/ GM-Tg-felg-MP0558-Ab-2Anti-Feline GRID1 monoclonal antibodyFeline
GM-Tg-cang-MP0558-Ab-1/ GM-Tg-cang-MP0558-Ab-2Anti-Canine GRID1 monoclonal antibodyCanine
GM-Tg-bovg-MP0558-Ab-1/ GM-Tg-bovg-MP0558-Ab-2Anti-Bovine GRID1 monoclonal antibodyBovine
GM-Tg-equg-MP0558-Ab-1/ GM-Tg-equg-MP0558-Ab-2Anti-Equine GRID1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0558-Ab-1/ GM-Tg-hg-MP0558-Ab-2; GM-Tg-rg-MP0558-Ab-1/ GM-Tg-rg-MP0558-Ab-2;
GM-Tg-mg-MP0558-Ab-1/ GM-Tg-mg-MP0558-Ab-2; GM-Tg-cynog-MP0558-Ab-1/ GM-Tg-cynog-MP0558-Ab-2;
GM-Tg-felg-MP0558-Ab-1/ GM-Tg-felg-MP0558-Ab-2; GM-Tg-cang-MP0558-Ab-1/ GM-Tg-cang-MP0558-Ab-2;
GM-Tg-bovg-MP0558-Ab-1/ GM-Tg-bovg-MP0558-Ab-2; GM-Tg-equg-MP0558-Ab-1/ GM-Tg-equg-MP0558-Ab-2
Products NameAnti-GRID1 monoclonal antibody
Formatmab
Target NameGRID1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GRID1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GRID1/ GluD1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm003638mouse Grid1 Lentivirus plasmid
    ORF Viral VectorvGMLPm003638mouse Grid1 Lentivirus particle


    Target information

    Target IDGM-MP0558
    Target NameGRID1
    Gene ID2894,14803,79219,697629,489075,101088275,100337106,100064635
    Gene Symbol and SynonymsGluD1,GluD1-b,GluRdelta1,GRID1
    Uniprot AccessionQ9ULK0,Q62640
    Uniprot Entry NameGRID1_HUMAN,GRID1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000182771
    Target ClassificationIon Channel

    The target: GRID1, gene name: GRID1, also named as GluD1. This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity.[provided by RefSeq, Jan 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.