Anti-NMD3A/ GRIN3A/ GluN3A monoclonal antibody

Anti-NMD3A/ GRIN3A/ GluN3A antibody for FACS & in-vivo assay

Target products collectionGo to GRIN3A/GRIN3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0560-Ab-1/ GM-Tg-hg-MP0560-Ab-2Anti-Human GRIN3A monoclonal antibodyHuman
GM-Tg-rg-MP0560-Ab-1/ GM-Tg-rg-MP0560-Ab-2Anti-Rat GRIN3A monoclonal antibodyRat
GM-Tg-mg-MP0560-Ab-1/ GM-Tg-mg-MP0560-Ab-2Anti-Mouse GRIN3A monoclonal antibodyMouse
GM-Tg-cynog-MP0560-Ab-1/ GM-Tg-cynog-MP0560-Ab-2Anti-Cynomolgus/ Rhesus macaque GRIN3A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0560-Ab-1/ GM-Tg-felg-MP0560-Ab-2Anti-Feline GRIN3A monoclonal antibodyFeline
GM-Tg-cang-MP0560-Ab-1/ GM-Tg-cang-MP0560-Ab-2Anti-Canine GRIN3A monoclonal antibodyCanine
GM-Tg-bovg-MP0560-Ab-1/ GM-Tg-bovg-MP0560-Ab-2Anti-Bovine GRIN3A monoclonal antibodyBovine
GM-Tg-equg-MP0560-Ab-1/ GM-Tg-equg-MP0560-Ab-2Anti-Equine GRIN3A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0560-Ab-1/ GM-Tg-hg-MP0560-Ab-2; GM-Tg-rg-MP0560-Ab-1/ GM-Tg-rg-MP0560-Ab-2;
GM-Tg-mg-MP0560-Ab-1/ GM-Tg-mg-MP0560-Ab-2; GM-Tg-cynog-MP0560-Ab-1/ GM-Tg-cynog-MP0560-Ab-2;
GM-Tg-felg-MP0560-Ab-1/ GM-Tg-felg-MP0560-Ab-2; GM-Tg-cang-MP0560-Ab-1/ GM-Tg-cang-MP0560-Ab-2;
GM-Tg-bovg-MP0560-Ab-1/ GM-Tg-bovg-MP0560-Ab-2; GM-Tg-equg-MP0560-Ab-1/ GM-Tg-equg-MP0560-Ab-2
Products NameAnti-GRIN3A monoclonal antibody
Formatmab
Target NameGRIN3A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GRIN3A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NMD3A/ GRIN3A/ GluN3A VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0560
    Target NameGRIN3A
    Gene ID116443,242443,191573,716892,474789,101098262,100295209,100062954
    Gene Symbol and Synonyms6430537F04,A830097C19Rik,chi-1,GluN3A,GRIN3A,mKIAA1973,NMDAR-L,NMDAR3A,NR3,NR3A
    Uniprot AccessionQ8TCU5,Q9R1M7
    Uniprot Entry NameNMD3A_HUMAN,NMD3A_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000198785
    Target ClassificationN/A

    The target: GRIN3A, gene name: GRIN3A, also named as GluN3A, NMDAR-L, NR3A. This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by modulating NMDA receptor activity. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.