Anti-GSG1L/ PRO19651 monoclonal antibody

Anti-GSG1L/ PRO19651 antibody for FACS & in-vivo assay

Target products collectionGo to GSG1L/GSG1L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0563-Ab-1/ GM-Tg-hg-MP0563-Ab-2Anti-Human GSG1L monoclonal antibodyHuman
GM-Tg-rg-MP0563-Ab-1/ GM-Tg-rg-MP0563-Ab-2Anti-Rat GSG1L monoclonal antibodyRat
GM-Tg-mg-MP0563-Ab-1/ GM-Tg-mg-MP0563-Ab-2Anti-Mouse GSG1L monoclonal antibodyMouse
GM-Tg-cynog-MP0563-Ab-1/ GM-Tg-cynog-MP0563-Ab-2Anti-Cynomolgus/ Rhesus macaque GSG1L monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0563-Ab-1/ GM-Tg-felg-MP0563-Ab-2Anti-Feline GSG1L monoclonal antibodyFeline
GM-Tg-cang-MP0563-Ab-1/ GM-Tg-cang-MP0563-Ab-2Anti-Canine GSG1L monoclonal antibodyCanine
GM-Tg-bovg-MP0563-Ab-1/ GM-Tg-bovg-MP0563-Ab-2Anti-Bovine GSG1L monoclonal antibodyBovine
GM-Tg-equg-MP0563-Ab-1/ GM-Tg-equg-MP0563-Ab-2Anti-Equine GSG1L monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0563-Ab-1/ GM-Tg-hg-MP0563-Ab-2; GM-Tg-rg-MP0563-Ab-1/ GM-Tg-rg-MP0563-Ab-2;
GM-Tg-mg-MP0563-Ab-1/ GM-Tg-mg-MP0563-Ab-2; GM-Tg-cynog-MP0563-Ab-1/ GM-Tg-cynog-MP0563-Ab-2;
GM-Tg-felg-MP0563-Ab-1/ GM-Tg-felg-MP0563-Ab-2; GM-Tg-cang-MP0563-Ab-1/ GM-Tg-cang-MP0563-Ab-2;
GM-Tg-bovg-MP0563-Ab-1/ GM-Tg-bovg-MP0563-Ab-2; GM-Tg-equg-MP0563-Ab-1/ GM-Tg-equg-MP0563-Ab-2
Products NameAnti-GSG1L monoclonal antibody
Formatmab
Target NameGSG1L
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GSG1L benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GSG1L/ PRO19651 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0563
    Target NameGSG1L
    Gene ID146395,269994,499263,704237,607985,101093569,511049,100064490
    Gene Symbol and SynonymsC230098I05Rik,g1l,G630023A01Rik,Gm637,GSG1L,PRO19651,RGD1562278
    Uniprot AccessionQ6UXU4,D3ZK93
    Uniprot Entry NameGSG1L_HUMAN,GSG1L_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169181
    Target ClassificationN/A

    The target: GSG1L, gene name: GSG1L, also named as PRO19651. Predicted to be involved in regulation of AMPA receptor activity. Predicted to be located in postsynaptic density. Predicted to be active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and plasma membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.