Anti-GLPC/ GYPC/ CD236 monoclonal antibody

Anti-GLPC/ GYPC/ CD236 antibody for FACS & in-vivo assay

Target products collectionGo to GYPC/GYPC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0567-Ab-1/ GM-Tg-hg-MP0567-Ab-2Anti-Human GYPC monoclonal antibodyHuman
GM-Tg-rg-MP0567-Ab-1/ GM-Tg-rg-MP0567-Ab-2Anti-Rat GYPC monoclonal antibodyRat
GM-Tg-mg-MP0567-Ab-1/ GM-Tg-mg-MP0567-Ab-2Anti-Mouse GYPC monoclonal antibodyMouse
GM-Tg-cynog-MP0567-Ab-1/ GM-Tg-cynog-MP0567-Ab-2Anti-Cynomolgus/ Rhesus macaque GYPC monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0567-Ab-1/ GM-Tg-felg-MP0567-Ab-2Anti-Feline GYPC monoclonal antibodyFeline
GM-Tg-cang-MP0567-Ab-1/ GM-Tg-cang-MP0567-Ab-2Anti-Canine GYPC monoclonal antibodyCanine
GM-Tg-bovg-MP0567-Ab-1/ GM-Tg-bovg-MP0567-Ab-2Anti-Bovine GYPC monoclonal antibodyBovine
GM-Tg-equg-MP0567-Ab-1/ GM-Tg-equg-MP0567-Ab-2Anti-Equine GYPC monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0567-Ab-1/ GM-Tg-hg-MP0567-Ab-2; GM-Tg-rg-MP0567-Ab-1/ GM-Tg-rg-MP0567-Ab-2;
GM-Tg-mg-MP0567-Ab-1/ GM-Tg-mg-MP0567-Ab-2; GM-Tg-cynog-MP0567-Ab-1/ GM-Tg-cynog-MP0567-Ab-2;
GM-Tg-felg-MP0567-Ab-1/ GM-Tg-felg-MP0567-Ab-2; GM-Tg-cang-MP0567-Ab-1/ GM-Tg-cang-MP0567-Ab-2;
GM-Tg-bovg-MP0567-Ab-1/ GM-Tg-bovg-MP0567-Ab-2; GM-Tg-equg-MP0567-Ab-1/ GM-Tg-equg-MP0567-Ab-2
Products NameAnti-GYPC monoclonal antibody
Formatmab
Target NameGYPC
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GYPC benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GLPC/ GYPC/ CD236 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0567
    Target NameGYPC
    Gene ID2995,71683,364837,712092,609898,101097411,444863,100630761
    Gene Symbol and Synonyms0610037F22Rik,CD236,CD236R,GE,GPC,GPD,GYPC,GYPD,PAS-2,PAS-2'
    Uniprot AccessionP04921,Q6XFR6
    Uniprot Entry NameGLPC_HUMAN,GLPC_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000136732
    Target ClassificationN/A

    The target: GYPC, gene name: GYPC, also named as CD236, CD236R, GE, GE:GPC:GPD:GYPD, GPC, GPD, GYPD, PAS-2, PAS-2'. Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.