Anti-HYAS3/ HAS3 monoclonal antibody

Anti-HYAS3/ HAS3 antibody for FACS & in-vivo assay

Target products collectionGo to HAS3/HAS3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0571-Ab-1/ GM-Tg-hg-MP0571-Ab-2Anti-Human HAS3 monoclonal antibodyHuman
GM-Tg-rg-MP0571-Ab-1/ GM-Tg-rg-MP0571-Ab-2Anti-Rat HAS3 monoclonal antibodyRat
GM-Tg-mg-MP0571-Ab-1/ GM-Tg-mg-MP0571-Ab-2Anti-Mouse HAS3 monoclonal antibodyMouse
GM-Tg-cynog-MP0571-Ab-1/ GM-Tg-cynog-MP0571-Ab-2Anti-Cynomolgus/ Rhesus macaque HAS3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0571-Ab-1/ GM-Tg-felg-MP0571-Ab-2Anti-Feline HAS3 monoclonal antibodyFeline
GM-Tg-cang-MP0571-Ab-1/ GM-Tg-cang-MP0571-Ab-2Anti-Canine HAS3 monoclonal antibodyCanine
GM-Tg-bovg-MP0571-Ab-1/ GM-Tg-bovg-MP0571-Ab-2Anti-Bovine HAS3 monoclonal antibodyBovine
GM-Tg-equg-MP0571-Ab-1/ GM-Tg-equg-MP0571-Ab-2Anti-Equine HAS3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0571-Ab-1/ GM-Tg-hg-MP0571-Ab-2; GM-Tg-rg-MP0571-Ab-1/ GM-Tg-rg-MP0571-Ab-2;
GM-Tg-mg-MP0571-Ab-1/ GM-Tg-mg-MP0571-Ab-2; GM-Tg-cynog-MP0571-Ab-1/ GM-Tg-cynog-MP0571-Ab-2;
GM-Tg-felg-MP0571-Ab-1/ GM-Tg-felg-MP0571-Ab-2; GM-Tg-cang-MP0571-Ab-1/ GM-Tg-cang-MP0571-Ab-2;
GM-Tg-bovg-MP0571-Ab-1/ GM-Tg-bovg-MP0571-Ab-2; GM-Tg-equg-MP0571-Ab-1/ GM-Tg-equg-MP0571-Ab-2
Products NameAnti-HAS3 monoclonal antibody
Formatmab
Target NameHAS3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-HAS3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species HYAS3/ HAS3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0571
    Target NameHAS3
    Gene ID3038,15118,266805,704121,489739,101096124,286824,100066947
    Gene Symbol and SynonymsHAS3
    Uniprot AccessionO00219
    Uniprot Entry NameHYAS3_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000103044
    Target ClassificationN/A

    The target: HAS3, gene name: HAS3, also named as . The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.