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Anti-IFI6/6-16/ FAM14C monoclonal antibody
Anti-IFI6/6-16/ FAM14C antibody for FACS & in-vivo assay
Go to IFI6/IFI6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0601-Ab-1/ GM-Tg-hg-MP0601-Ab-2 | Anti-Human IFI6 monoclonal antibody | Human |
| GM-Tg-rg-MP0601-Ab-1/ GM-Tg-rg-MP0601-Ab-2 | Anti-Rat IFI6 monoclonal antibody | Rat |
| GM-Tg-mg-MP0601-Ab-1/ GM-Tg-mg-MP0601-Ab-2 | Anti-Mouse IFI6 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0601-Ab-1/ GM-Tg-cynog-MP0601-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IFI6 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0601-Ab-1/ GM-Tg-felg-MP0601-Ab-2 | Anti-Feline IFI6 monoclonal antibody | Feline |
| GM-Tg-cang-MP0601-Ab-1/ GM-Tg-cang-MP0601-Ab-2 | Anti-Canine IFI6 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0601-Ab-1/ GM-Tg-bovg-MP0601-Ab-2 | Anti-Bovine IFI6 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0601-Ab-1/ GM-Tg-equg-MP0601-Ab-2 | Anti-Equine IFI6 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0601-Ab-1/ GM-Tg-hg-MP0601-Ab-2; GM-Tg-rg-MP0601-Ab-1/ GM-Tg-rg-MP0601-Ab-2; GM-Tg-mg-MP0601-Ab-1/ GM-Tg-mg-MP0601-Ab-2; GM-Tg-cynog-MP0601-Ab-1/ GM-Tg-cynog-MP0601-Ab-2; GM-Tg-felg-MP0601-Ab-1/ GM-Tg-felg-MP0601-Ab-2; GM-Tg-cang-MP0601-Ab-1/ GM-Tg-cang-MP0601-Ab-2; GM-Tg-bovg-MP0601-Ab-1/ GM-Tg-bovg-MP0601-Ab-2; GM-Tg-equg-MP0601-Ab-1/ GM-Tg-equg-MP0601-Ab-2 |
| Products Name | Anti-IFI6 monoclonal antibody |
| Format | mab |
| Target Name | IFI6 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IFI6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species IFI6/6-16/ FAM14C VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP000687 | human IFI6 Lentivirus particle |
| ORF Viral Vector | pGMLP000687 | human IFI6 Lentivirus plasmid |
Target information
| Target ID | GM-MP0601 |
| Target Name | IFI6 |
| Gene ID | 2537,716339,478170,101089878,512913,100070860 |
| Gene Symbol and Synonyms | 6-16,FAM14C,G1P3,IFI-6-16,IFI6,IFI616 |
| Uniprot Accession | P09912,Q6IED8 |
| Uniprot Entry Name | IFI6_HUMAN,IFI6_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000126709 |
| Target Classification | N/A |
The target: IFI6, gene name: IFI6, also named as 6-16, FAM14C, G1P3, IFI-6-1616, IFI6. This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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