Anti-IRPL2/ IL1RAPL2/ IL-1R9 monoclonal antibody

Anti-IRPL2/ IL1RAPL2/ IL-1R9 antibody for FACS & in-vivo assay

Target products collectionGo to IL1RAPL2/IL1RAPL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0621-Ab-1/ GM-Tg-hg-MP0621-Ab-2Anti-Human IL1RAPL2 monoclonal antibodyHuman
GM-Tg-rg-MP0621-Ab-1/ GM-Tg-rg-MP0621-Ab-2Anti-Rat IL1RAPL2 monoclonal antibodyRat
GM-Tg-mg-MP0621-Ab-1/ GM-Tg-mg-MP0621-Ab-2Anti-Mouse IL1RAPL2 monoclonal antibodyMouse
GM-Tg-cynog-MP0621-Ab-1/ GM-Tg-cynog-MP0621-Ab-2Anti-Cynomolgus/ Rhesus macaque IL1RAPL2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0621-Ab-1/ GM-Tg-felg-MP0621-Ab-2Anti-Feline IL1RAPL2 monoclonal antibodyFeline
GM-Tg-cang-MP0621-Ab-1/ GM-Tg-cang-MP0621-Ab-2Anti-Canine IL1RAPL2 monoclonal antibodyCanine
GM-Tg-bovg-MP0621-Ab-1/ GM-Tg-bovg-MP0621-Ab-2Anti-Bovine IL1RAPL2 monoclonal antibodyBovine
GM-Tg-equg-MP0621-Ab-1/ GM-Tg-equg-MP0621-Ab-2Anti-Equine IL1RAPL2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0621-Ab-1/ GM-Tg-hg-MP0621-Ab-2; GM-Tg-rg-MP0621-Ab-1/ GM-Tg-rg-MP0621-Ab-2;
GM-Tg-mg-MP0621-Ab-1/ GM-Tg-mg-MP0621-Ab-2; GM-Tg-cynog-MP0621-Ab-1/ GM-Tg-cynog-MP0621-Ab-2;
GM-Tg-felg-MP0621-Ab-1/ GM-Tg-felg-MP0621-Ab-2; GM-Tg-cang-MP0621-Ab-1/ GM-Tg-cang-MP0621-Ab-2;
GM-Tg-bovg-MP0621-Ab-1/ GM-Tg-bovg-MP0621-Ab-2; GM-Tg-equg-MP0621-Ab-1/ GM-Tg-equg-MP0621-Ab-2
Products NameAnti-IL1RAPL2 monoclonal antibody
Formatmab
Target NameIL1RAPL2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IL1RAPL2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species IRPL2/ IL1RAPL2/ IL-1R9 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0621
    Target NameIL1RAPL2
    Gene ID26280,60367,300913,699765,492045,101100037,523444,100055002
    Gene Symbol and SynonymsIL-1R9,IL1R9,IL1RAPL-2,IL1RAPL2,RGD1561761,TIGIRR-1
    Uniprot AccessionQ9NP60
    Uniprot Entry NameIRPL2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000189108
    Target ClassificationN/A

    The target: IL1RAPL2, gene name: IL1RAPL2, also named as IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1. The protein encoded by this gene is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accessory protein-like 1 (IL1RAPL1). This gene and IL1RAPL1 are located at a region on chromosome X that is associated with X-linked non-syndromic cognitive disability. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.