- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-IL2RG/ CD132/ CIDX monoclonal antibody
Anti-IL2RG/ CD132/ CIDX antibody for FACS & in-vivo assay
Go to IL2RG/IL2RG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0627-Ab-1/ GM-Tg-hg-MP0627-Ab-2 | Anti-Human IL2RG monoclonal antibody | Human |
| GM-Tg-rg-MP0627-Ab-1/ GM-Tg-rg-MP0627-Ab-2 | Anti-Rat IL2RG monoclonal antibody | Rat |
| GM-Tg-mg-MP0627-Ab-1/ GM-Tg-mg-MP0627-Ab-2 | Anti-Mouse IL2RG monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0627-Ab-1/ GM-Tg-cynog-MP0627-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IL2RG monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0627-Ab-1/ GM-Tg-felg-MP0627-Ab-2 | Anti-Feline IL2RG monoclonal antibody | Feline |
| GM-Tg-cang-MP0627-Ab-1/ GM-Tg-cang-MP0627-Ab-2 | Anti-Canine IL2RG monoclonal antibody | Canine |
| GM-Tg-bovg-MP0627-Ab-1/ GM-Tg-bovg-MP0627-Ab-2 | Anti-Bovine IL2RG monoclonal antibody | Bovine |
| GM-Tg-equg-MP0627-Ab-1/ GM-Tg-equg-MP0627-Ab-2 | Anti-Equine IL2RG monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0627-Ab-1/ GM-Tg-hg-MP0627-Ab-2; GM-Tg-rg-MP0627-Ab-1/ GM-Tg-rg-MP0627-Ab-2; GM-Tg-mg-MP0627-Ab-1/ GM-Tg-mg-MP0627-Ab-2; GM-Tg-cynog-MP0627-Ab-1/ GM-Tg-cynog-MP0627-Ab-2; GM-Tg-felg-MP0627-Ab-1/ GM-Tg-felg-MP0627-Ab-2; GM-Tg-cang-MP0627-Ab-1/ GM-Tg-cang-MP0627-Ab-2; GM-Tg-bovg-MP0627-Ab-1/ GM-Tg-bovg-MP0627-Ab-2; GM-Tg-equg-MP0627-Ab-1/ GM-Tg-equg-MP0627-Ab-2 |
| Products Name | Anti-IL2RG monoclonal antibody |
| Format | mab |
| Target Name | IL2RG |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL2RG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species IL2RG/ CD132/ CIDX VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP000448 | human IL2RG Lentivirus particle |
| ORF Viral Vector | pGMLP000448 | human IL2RG Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001973 | mouse Il2rg Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001973 | mouse Il2rg Lentivirus particle |
Target information
| Target ID | GM-MP0627 |
| Target Name | IL2RG |
| Gene ID | 3561,16186,140924,641338,403851,101090239,281862,100055911 |
| Gene Symbol and Synonyms | Ab2-183,CD132,CIDX,gamma(c),gc,IL-2RG,IL2RG,IMD4,P64,SCIDX,SCIDX1,[g]c |
| Uniprot Accession | P31785,P40321,Q95118 |
| Uniprot Entry Name | IL2RG_HUMAN,IL2RG_CANLF,IL2RG_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000147168 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: IL2RG, gene name: IL2RG, also named as CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1. The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
