Anti-ILDR1/ DFNB42alpha/ ILDR1alpha' monoclonal antibody

Anti-ILDR1/ DFNB42alpha/ ILDR1alpha' antibody for FACS & in-vivo assay

Target products collectionGo to ILDR1/ILDR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0628-Ab-1/ GM-Tg-hg-MP0628-Ab-2Anti-Human ILDR1 monoclonal antibodyHuman
GM-Tg-rg-MP0628-Ab-1/ GM-Tg-rg-MP0628-Ab-2Anti-Rat ILDR1 monoclonal antibodyRat
GM-Tg-mg-MP0628-Ab-1/ GM-Tg-mg-MP0628-Ab-2Anti-Mouse ILDR1 monoclonal antibodyMouse
GM-Tg-cynog-MP0628-Ab-1/ GM-Tg-cynog-MP0628-Ab-2Anti-Cynomolgus/ Rhesus macaque ILDR1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0628-Ab-1/ GM-Tg-felg-MP0628-Ab-2Anti-Feline ILDR1 monoclonal antibodyFeline
GM-Tg-cang-MP0628-Ab-1/ GM-Tg-cang-MP0628-Ab-2Anti-Canine ILDR1 monoclonal antibodyCanine
GM-Tg-bovg-MP0628-Ab-1/ GM-Tg-bovg-MP0628-Ab-2Anti-Bovine ILDR1 monoclonal antibodyBovine
GM-Tg-equg-MP0628-Ab-1/ GM-Tg-equg-MP0628-Ab-2Anti-Equine ILDR1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0628-Ab-1/ GM-Tg-hg-MP0628-Ab-2; GM-Tg-rg-MP0628-Ab-1/ GM-Tg-rg-MP0628-Ab-2;
GM-Tg-mg-MP0628-Ab-1/ GM-Tg-mg-MP0628-Ab-2; GM-Tg-cynog-MP0628-Ab-1/ GM-Tg-cynog-MP0628-Ab-2;
GM-Tg-felg-MP0628-Ab-1/ GM-Tg-felg-MP0628-Ab-2; GM-Tg-cang-MP0628-Ab-1/ GM-Tg-cang-MP0628-Ab-2;
GM-Tg-bovg-MP0628-Ab-1/ GM-Tg-bovg-MP0628-Ab-2; GM-Tg-equg-MP0628-Ab-1/ GM-Tg-equg-MP0628-Ab-2
Products NameAnti-ILDR1 monoclonal antibody
Formatmab
Target NameILDR1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ILDR1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ILDR1/ DFNB42alpha/ ILDR1alpha' VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP0628
    Target NameILDR1
    Gene ID286676,106347,303914,714332,608570,101090132,538495,100070692
    Gene Symbol and SynonymsDFNB42,ILDR1,ILDR1alpha,ILDR1alpha',ILDR1beta,RGD1307792
    Uniprot AccessionQ86SU0
    Uniprot Entry NameILDR1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000145103
    Target ClassificationN/A

    The target: ILDR1, gene name: ILDR1, also named as DFNB42alpha, ILDR1alpha', ILDR1beta, ILDR1. This gene encodes a protein that contains an immunoglobulin-like domain. The encoded protein may function as a multimeric receptor at the cell surface. The expression of this gene may be a diagnostic marker for cancer progression. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.